ICP27 protein of Marek's disease virus interacts with SR proteins and inhibits the splicing of cellular telomerase chTERT and viral vIL8 transcripts

All herpesviruses have a post-transcriptional regulatory protein that prevents precursor mRNA splicing and leads to the shutting off of host protein synthesis. The ICP27 protein of herpes simplex virus 1 (HSV-1) is the prototype of these proteins. Marek's disease virus (MDV-1), an alphaherpesvi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of general virology 2011-06, Vol.92 (Pt 6), p.1273-1278
Hauptverfasser:	AMOR, S, STRASSHEIM, S, DAMBRINE, G, REMY, S, RASSCHAERT, D, LAURENT, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Cell Line Cell Nucleus - genetics Cell Nucleus - metabolism Chickens Down-Regulation Fundamental and applied biological sciences. Psychology Herpesvirus 2, Gallid - genetics Herpesvirus 2, Gallid - metabolism Interleukin-8 - genetics Interleukin-8 - metabolism Life Sciences Marek Disease - enzymology Marek Disease - genetics Marek Disease - virology Microbiology Microbiology and Parasitology Miscellaneous Molecular Sequence Data Protein Binding Protein Transport RNA Splicing Spliceosomes - genetics Spliceosomes - metabolism Telomerase - genetics Telomerase - metabolism Viral Proteins - genetics Viral Proteins - metabolism Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!