Visualizing and Profiling Lipids in the OVLT of Fat‑1 and Wild Type Mouse Brains during LPS-Induced Systemic Inflammation Using AP-SMALDI MSI

Lipids, including omega-3 polyunsaturated fatty acids (n-3-PUFAs), modulate brain-intrinsic inflammation during systemic inflammation. The vascular organ of the lamina terminalis (OVLT) is a brain structure important for immune-to-brain communication. We, therefore, aimed to profile the distribution...

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Veröffentlicht in:ACS chemical neuroscience 2019-10, Vol.10 (10), p.4394-4406
Hauptverfasser: Bredehöft, Janne, Bhandari, Dhaka Ram, Pflieger, Fabian Johannes, Schulz, Sabine, Kang, Jing X, Layé, Sophie, Roth, Joachim, Gerstberger, Rüdiger, Mayer, Konstantin, Spengler, Bernhard, Rummel, Christoph
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Sprache:eng
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