Validity of surrogate endpoints assessing central venous catheter-related infection: evidence from individual- and study-level analyses

The prevention of catheter-related bloodstream infection (CRBSI) has been an area of intense research, but the heterogeneity of endpoints used to define catheter infection makes the interpretation of randomized controlled trials (RCTs) problematic. The aim of this study was to determine the validity...

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Veröffentlicht in:	Clinical microbiology and infection 2020-05, Vol.26 (5), p.563-571
Hauptverfasser:	de Grooth, H.J., Timsit, J.-F., Mermel, L., Mimoz, O., Buetti, N., du Cheyron, D., Oudemans-van Straaten, H.M., Parienti, J.-J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteraemia Bacteremia - diagnosis Bacteremia - therapy Biomarkers - analysis Blood culture Catheter-related infections Catheter-Related Infections - diagnosis Catheter-Related Infections - therapy Central Venous Catheters - adverse effects Central Venous Catheters - microbiology Human health and pathology Humans Infectious diseases Life Sciences Network Meta-Analysis Patient Outcome Assessment Pharmaceutical sciences Practice Guidelines as Topic Reproducibility of Results Surrogate endpoints Vascular access devices
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