Olfaction: A potential cognitive marker of psychiatric disorders
Cognitive deficits are well documented in psychiatric disorders, particularly in schizophrenia and depression. Cognitive activity roots in perceptions. However, research on sensorial alterations in psychiatric conditions has mainly focused on visual or auditory processes and less on olfaction. Here,...
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| Veröffentlicht in: | Neuroscience and biobehavioral reviews 2008-09, Vol.32 (7), p.1315-1325 |
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| creator | Atanasova, Boriana Graux, Jérôme El Hage, Wissam Hommet, Caroline Camus, Vincent Belzung, Catherine |
| description | Cognitive deficits are well documented in psychiatric disorders, particularly in schizophrenia and depression. Cognitive activity roots in perceptions. However, research on sensorial alterations in psychiatric conditions has mainly focused on visual or auditory processes and less on olfaction. Here, we examine data on olfactory deficits in psychiatric patients using a systematic review of recent publications. Schizophrenic patients are mainly characterized by no reliable change in odour sensitivity and by a deficit in odour identification, recognition and discrimination. Depressed patients principally exhibit a deficit in the hedonic aspects of this perception, even if, in some case, alterations in sensitivity or identification are also found. Changes in odour perception are also found in dementia and in some neurodegenerative disease, but in this case alterations concern all aspects of the sensorial experience (detection threshold, identification and recognition). Taken together, these data indicate that olfactory abnormalities might be a marker of psychiatric conditions, with a specific pattern for each disease. |
| doi_str_mv | 10.1016/j.neubiorev.2008.05.003 |
| format | Article |
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Cognitive activity roots in perceptions. However, research on sensorial alterations in psychiatric conditions has mainly focused on visual or auditory processes and less on olfaction. Here, we examine data on olfactory deficits in psychiatric patients using a systematic review of recent publications. Schizophrenic patients are mainly characterized by no reliable change in odour sensitivity and by a deficit in odour identification, recognition and discrimination. Depressed patients principally exhibit a deficit in the hedonic aspects of this perception, even if, in some case, alterations in sensitivity or identification are also found. Changes in odour perception are also found in dementia and in some neurodegenerative disease, but in this case alterations concern all aspects of the sensorial experience (detection threshold, identification and recognition). 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| subjects | Biomarkers Brain - physiopathology Cognition Disorders - complications Cognition Disorders - physiopathology Cognitive bias Dementia - complications Dementia - physiopathology Depression Depressive Disorder - complications Depressive Disorder - physiopathology Discrimination (Psychology) Humans Life Sciences Marker Mental Disorders - complications Mental Disorders - physiopathology Neurobiology Neurodegenerative Diseases - complications Neurodegenerative Diseases - physiopathology Neurons and Cognition Olfaction Olfaction Disorders - complications Olfaction Disorders - physiopathology Recognition (Psychology) Schizophrenia Schizophrenia - complications Schizophrenia - physiopathology |
| title | Olfaction: A potential cognitive marker of psychiatric disorders |
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