Toxicities associated with chemotherapy regimens containing a fluoropyrimidine: A real-life evaluation in France

Despite fluoropyrimidines (FPs) constituting the main component of the chemotherapy combination protocols in 50% of chemotherapies for solid tumour treatments, incidence data for FP-related toxicity are poorly documented in real life. This study evaluated the number of patients receiving FP-based ch...

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Veröffentlicht in:	European journal of cancer (1990) 2020-01, Vol.124, p.37-46
Hauptverfasser:	Barin-Le Guellec, Chantal, Lafay-Chebassier, Claire, Ingrand, Isabelle, Tournamille, Jean-François, Boudet, Adeline, Lanoue, Mary-Christine, Defossez, Gautier, Ingrand, Pierre, Perault-Pochat, Marie-Christine, Etienne-Grimaldi, Marie-Christine
Format:	Artikel
Sprache:	eng
Schlagworte:	5 Fluorouracil Adverse effects Antineoplastic Combined Chemotherapy Protocols - toxicity Breast Breast cancer Capecitabine Capecitabine - administration & dosage Capecitabine - toxicity Catabolism Chemotherapy Confidence intervals Digestive system Dihydropyrimidine dehydrogenase Dihydrouracil Dehydrogenase (NADP) - toxicity Fatalities Female Fluoropyrimidine Fluorouracil - administration & dosage Fluorouracil - toxicity France Head & neck cancer Head and neck Humans Life Sciences Male Medication Adherence Organoplatinum Compounds - toxicity Pharmaceutical sciences Pharmacology Pharmacovigilance Prognosis Public health Solid tumors Toxic death Toxicity Tumors
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