Genetic Ablation of Caveolin-1 Confers Protection Against Atherosclerosis

OBJECTIVE—The development of atherosclerosis is a process characterized by the accumulation of lipids in the form of modified lipoproteins in the subendothelial space. This initiating step is followed by the subsequent recruitment and proliferation of other cell types, including monocytes/macrophage...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2004-01, Vol.24 (1), p.98-105
Hauptverfasser:	Frank, Philippe G, Lee, Hyangkyu, Park, David S, Tandon, Narendra N, Scherer, Phillip E, Lisanti, Michael P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aortic Diseases - genetics Aortic Diseases - prevention & control Apolipoproteins E - deficiency Apolipoproteins E - genetics Apolipoproteins E - physiology Arteriosclerosis - genetics Arteriosclerosis - prevention & control Atherosclerosis (general aspects, experimental research) Biochemistry Biochemistry, Molecular Biology Biological and medical sciences Blood and lymphatic vessels Cancer Cardiology. Vascular system Caveolae - physiology Caveolin 1 Caveolins - deficiency Caveolins - genetics Caveolins - physiology CD36 Antigens - biosynthesis CD36 Antigens - genetics Cell Behavior Cellular Biology Cholesterol, Dietary - toxicity Crosses, Genetic Diet, Atherogenic Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Food and Nutrition Hypercholesterolemia - genetics Life Sciences Lipoproteins - blood Male Medical sciences Mice Mice, Inbred C57BL Mice, Knockout Molecular biology Subcellular Processes Vascular Cell Adhesion Molecule-1 - biosynthesis Vascular Cell Adhesion Molecule-1 - genetics
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