Inhibition of Rainbow Trout (Oncorhynchus mykiss) Estrogen Receptor Activity by Cadmium

This study was conducted to determine if the cadmium-mediated inhibition of vitellogenesis observed in fish collected from contaminated areas or undergoing experimental exposure to cadmium correlated with modification in the transcriptional activity of the estrogen receptor. A recombinant yeast syst...

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Veröffentlicht in:	Biology of reproduction 2000-07, Vol.63 (1), p.259-266
Hauptverfasser:	LE GUEVEL, R, PETIT, F. G, LE GOFF, P, METIVIER, R, VALOTAIRE, Y, PAKDEL, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Biological and medical sciences Cadmium - pharmacology Cellular Biology Chemical and industrial products toxicology. Toxic occupational diseases Dimerization DNA - metabolism Estradiol - metabolism Furylfuramide - metabolism Humans Life Sciences Medical sciences Metals and various inorganic compounds Metals, Heavy - pharmacology Oncorhynchus mykiss - genetics Oncorhynchus mykiss - metabolism Receptors, Estradiol - antagonists & inhibitors Receptors, Estradiol - genetics Receptors, Estrogen - antagonists & inhibitors Receptors, Estrogen - genetics Receptors, Estrogen - metabolism Recombinant Proteins - drug effects Recombinant Proteins - genetics Recombinant Proteins - metabolism Toxicology Transcription, Genetic Vitellogenins - drug effects Vitellogenins - metabolism Yeasts - genetics
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