Differential activation of Stat3 and Stat5 by distinct regions of the growth hormone receptor

Abstract The GH receptor (GHR) is a member of the cytokine receptor superfamily; its signaling involves the activation of Janus tyrosine kinases (JAK2) and Stat (signal transducers and activators of transcription) transcription factors. Using truncated and tyrosine mutants of the receptor, we show t...

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Veröffentlicht in:Molecular endocrinology (Baltimore, Md.) Md.), 1996-08, Vol.10 (8), p.998-1009
Hauptverfasser: Sotiropoulos, A, Moutoussamy, S, Renaudie, F, Clauss, M, Kayser, C, Gouilleux, F, Kelly, P A, Finidori, J
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Sprache:eng
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