Local production of tenascin-C acts as a trigger for monocyte/macrophage recruitment that provokes cardiac dysfunction
Abstract Aims Tenascin-C (TNC) is an endogenous danger signal molecule strongly associated with inflammatory diseases and with poor outcome in patients with cardiomyopathies. Its function within pathological cardiac tissue during pressure overload remains poorly understood. Methods and results We sh...
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Veröffentlicht in: | Cardiovascular research 2018-01, Vol.114 (1), p.123-137 |
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Hauptverfasser: | , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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