Synthesis of Molecularly Encoded Oligomers Using a Chemoselective "AB + CD" Iterative Approach

A library of eight sequence‐defined model oligomers, whose sequence is based on a (0,1) binary code, is prepared through chemoselective repeating cycles of amidification and copper‐assisted alkyne‐azide cycloaddition reactions from a non‐modified Wang resin. This library is constructed from two AB (...

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Veröffentlicht in:Macromolecular rapid communications. 2014-01, Vol.35 (2), p.141-145
Hauptverfasser: Trinh, Thanh Tam, Oswald, Laurence, Chan-Seng, Delphine, Lutz, Jean-François
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Sprache:eng
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