Drp1 polymerization stabilizes curved tubular membranes similar to those of constricted mitochondria

Dynamin-related protein 1 (Drp1), an 80 kDa mechanochemical GTPase of the dynamin superfamily, is required for mitochondrial division in mammals. Despite the role of Drp1 dysfunction in human disease, its molecular mechanism remains poorly understood. Here, we examined the effect of Drp1 on membrane...

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Veröffentlicht in:	Journal of cell science 2018-04, Vol.132 (4)
Hauptverfasser:	Ugarte-Uribe, Begoña, Prévost, Coline, Das, Kushal Kumar, Bassereau, Patricia, García-Sáez, Ana J
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry, Molecular Biology Biophysics Cellular Biology Condensed Matter Life Sciences Physics Soft Condensed Matter Subcellular Processes
Online-Zugang:	Volltext
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