“HFP” Fluorinated Cationic Lipids for Enhanced Lipoplex Stability and Gene Delivery

Although a great number of cationic lipids have been designed and evaluated as gene delivery systems, there is still a need for improvement of nonviral vectors. Recently, cationic lipids incorporating terminal fluoroalkyl segments (“FHP” lipids) have been described to display remarkable transfection...

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Veröffentlicht in:Bioconjugate chemistry 2010-02, Vol.21 (2), p.360-371
Hauptverfasser: Klein, Emmanuel, Ciobanu, Miahala, Klein, Jérôme, Machi, Valérie, Leborgne, Christian, Vandamme, Thierry, Frisch, Benoît, Pons, Françoise, Kichler, Antoine, Zuber, Guy, Lebeau, Luc
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Sprache:eng
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