Clinical value of chip-based digital-PCR platform for the detection of circulating DNA in metastatic colorectal cancer

Abstract Background The detection of circulating DNA is considered a promising strategy in cancer patients. Digital PCR has emerged as a sensitive method able to quantify both circulating free and tumour DNA. Aim The aim of this study was to prospectively evaluate the clinical value of a chip-based...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Digestive and liver disease 2015-10, Vol.47 (10), p.884-890
Hauptverfasser:	Sefrioui, David, Sarafan-Vasseur, Nasrin, Beaussire, Ludivine, Baretti, Marina, Gangloff, Alice, Blanchard, France, Clatot, Florian, Sabourin, Jean-Christophe, Sesboüé, Richard, Frebourg, Thierry, Michel, Pierre, Di Fiore, Frédéric
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - blood Circulating tumour DNA Colorectal Neoplasms - diagnosis Colorectal Neoplasms - mortality Colorectal Neoplasms - pathology DNA, Neoplasm - blood DNA, Neoplasm - isolation & purification Female Gastroenterology and Hepatology Genes, ras Humans K-ras mutation Kaplan-Meier Estimate Life Sciences Male Middle Aged Mutation Neoplasm Metastasis Polymerase Chain Reaction - methods Prognosis Prognostic value Survival Rate Ultrasensitive detection method
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!