Mitochondria in Developmental and Adult Neurogenesis
Generation of new neurons is a tightly regulated process that involves several intrinsic and extrinsic factors. Among them, a metabolic switch from glycolysis to oxidative phosphorylation, together with mitochondrial remodeling, has emerged as crucial actors of neurogenesis. However, although accumu...
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| Veröffentlicht in: | Neurotoxicity research 2019-08, Vol.36 (2), p.257-267 |
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| container_title | Neurotoxicity research |
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| creator | Arrázola, Macarena S. Andraini, Trinovita Szelechowski, Marion Mouledous, Lionel Arnauné-Pelloquin, Laetitia Davezac, Noélie Belenguer, Pascale Rampon, Claire Miquel, Marie-Christine |
| description | Generation of new neurons is a tightly regulated process that involves several intrinsic and extrinsic factors. Among them, a metabolic switch from glycolysis to oxidative phosphorylation, together with mitochondrial remodeling, has emerged as crucial actors of neurogenesis. However, although accumulating data raise the importance of mitochondrial morphology and function in neural stem cell proliferation and differentiation during development, information regarding the contribution of mitochondria to adult neurogenesis processes remains limited. In the present review, we discuss recent evidence covering the importance of mitochondrial morphology, function, and energy metabolism in the regulation of neuronal development and adult neurogenesis, and their impact on memory processes. |
| doi_str_mv | 10.1007/s12640-018-9942-y |
| format | Article |
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In the present review, we discuss recent evidence covering the importance of mitochondrial morphology, function, and energy metabolism in the regulation of neuronal development and adult neurogenesis, and their impact on memory processes.</description><subject>Adult</subject><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Cell Differentiation - physiology</subject><subject>Humans</subject><subject>Life Sciences</subject><subject>Mitochondria - physiology</subject><subject>Neural Stem Cells - physiology</subject><subject>Neurobiology</subject><subject>Neurochemistry</subject><subject>Neurogenesis - physiology</subject><subject>Neurology</subject><subject>Neurons - physiology</subject><subject>Neurons and Cognition</subject><subject>Neurosciences</subject><subject>Original Article</subject><subject>Pharmacology/Toxicology</subject><issn>1029-8428</issn><issn>1476-3524</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kD9PwzAQxS0EoqXwAVhQVgaDz3acZKzKnyIVWGC2nNhuU6VOZSeV-u1xFOjIdE93793pfgjdAnkAQrLHAFRwggnkuCg4xcczNAWeCcxSys-jJrTAOaf5BF2FsCWEQiqySzRhgwIBU8Tf666tNq3TvlZJ7ZInczBNu98Z16kmUU4nc903XfJhet-ujTOhDtfowqommJvfOkPfL89fiyVefb6-LeYrXLEs77BIjRZCpfGayayynJY2rYBrBqkWZZkJVXLBbCG0BVUqarStWE4IB9DUApuh-3HvRjVy7-ud8kfZqlou5ys59AhlKRQZPQxeGL2Vb0Pwxp4CQORAS460ZKQlB1ryGDN3Y2bflzujT4k_PNFAR0OII7c2Xm7b3rv48z9bfwBMJ3Tr</recordid><startdate>20190801</startdate><enddate>20190801</enddate><creator>Arrázola, Macarena S.</creator><creator>Andraini, Trinovita</creator><creator>Szelechowski, Marion</creator><creator>Mouledous, Lionel</creator><creator>Arnauné-Pelloquin, Laetitia</creator><creator>Davezac, Noélie</creator><creator>Belenguer, Pascale</creator><creator>Rampon, Claire</creator><creator>Miquel, Marie-Christine</creator><general>Springer US</general><general>Springer Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0002-9332-2572</orcidid><orcidid>https://orcid.org/0000-0001-8551-8682</orcidid><orcidid>https://orcid.org/0000-0002-7675-3493</orcidid><orcidid>https://orcid.org/0000-0002-6034-6359</orcidid><orcidid>https://orcid.org/0000-0001-5284-4916</orcidid><orcidid>https://orcid.org/0000-0003-0229-5554</orcidid><orcidid>https://orcid.org/0000-0003-4264-7729</orcidid></search><sort><creationdate>20190801</creationdate><title>Mitochondria in Developmental and Adult Neurogenesis</title><author>Arrázola, Macarena S. ; Andraini, Trinovita ; Szelechowski, Marion ; Mouledous, Lionel ; Arnauné-Pelloquin, Laetitia ; Davezac, Noélie ; Belenguer, Pascale ; Rampon, Claire ; Miquel, Marie-Christine</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-65ed66a5302e7faf42bf5c14d315d6bb76ab463f96df1aba2edfc3800411d2f13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cell Biology</topic><topic>Cell Differentiation - physiology</topic><topic>Humans</topic><topic>Life Sciences</topic><topic>Mitochondria - physiology</topic><topic>Neural Stem Cells - physiology</topic><topic>Neurobiology</topic><topic>Neurochemistry</topic><topic>Neurogenesis - physiology</topic><topic>Neurology</topic><topic>Neurons - physiology</topic><topic>Neurons and Cognition</topic><topic>Neurosciences</topic><topic>Original Article</topic><topic>Pharmacology/Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arrázola, Macarena S.</creatorcontrib><creatorcontrib>Andraini, Trinovita</creatorcontrib><creatorcontrib>Szelechowski, Marion</creatorcontrib><creatorcontrib>Mouledous, Lionel</creatorcontrib><creatorcontrib>Arnauné-Pelloquin, Laetitia</creatorcontrib><creatorcontrib>Davezac, Noélie</creatorcontrib><creatorcontrib>Belenguer, Pascale</creatorcontrib><creatorcontrib>Rampon, Claire</creatorcontrib><creatorcontrib>Miquel, Marie-Christine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Neurotoxicity research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arrázola, Macarena S.</au><au>Andraini, Trinovita</au><au>Szelechowski, Marion</au><au>Mouledous, Lionel</au><au>Arnauné-Pelloquin, Laetitia</au><au>Davezac, Noélie</au><au>Belenguer, Pascale</au><au>Rampon, Claire</au><au>Miquel, Marie-Christine</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mitochondria in Developmental and Adult Neurogenesis</atitle><jtitle>Neurotoxicity research</jtitle><stitle>Neurotox Res</stitle><addtitle>Neurotox Res</addtitle><date>2019-08-01</date><risdate>2019</risdate><volume>36</volume><issue>2</issue><spage>257</spage><epage>267</epage><pages>257-267</pages><issn>1029-8428</issn><eissn>1476-3524</eissn><abstract>Generation of new neurons is a tightly regulated process that involves several intrinsic and extrinsic factors. 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| subjects | Adult Animals Biomedical and Life Sciences Biomedicine Cell Biology Cell Differentiation - physiology Humans Life Sciences Mitochondria - physiology Neural Stem Cells - physiology Neurobiology Neurochemistry Neurogenesis - physiology Neurology Neurons - physiology Neurons and Cognition Neurosciences Original Article Pharmacology/Toxicology |
| title | Mitochondria in Developmental and Adult Neurogenesis |
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