Quantification of Cellular Deoxyribonucleoside Triphosphates by Rolling Circle Amplification and Förster Resonance Energy Transfer

The quantification of cellular deoxyribonucleoside triphosphate (dNTP) levels is important for studying pathologies, genome integrity, DNA repair, and the efficacy of pharmacological drug treatments. Current standard methods, such as enzymatic assays or high-performance liquid chromatography, are co...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-11, Vol.91 (22), p.14561-14568
Hauptverfasser:	Qiu, Xue, Guittet, Olivier, Mingoes, Carlos, El Banna, Nadine, Huang, Meng-Er, Lepoivre, Michel, Hildebrandt, Niko
Format:	Artikel
Sprache:	eng
Schlagworte:	Amplification Analytical chemistry Assaying Biochemistry Biochemistry, Molecular Biology Chemistry Deoxyribonucleic acid DNA DNA repair Energy transfer Fluorescence resonance energy transfer Genomes High performance liquid chromatography Hydroxyurea Leukemia Life Sciences Liquid chromatography Pharmacology Resonance Time dependence
Online-Zugang:	Volltext
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