Notched T waves on Holter recordings enhance detection of patients with LQT2 (HERG) mutations

The 2 genes KCNQ1 (LQT1) and HERG (LQT2), encoding cardiac potassium channels, are the most common cause of the dominant long-QT syndrome (LQTS). In addition to QT-interval prolongation, notched T waves have been proposed as a phenotypic marker of LQTS patients. The T-wave morphology of carriers of...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2001-02, Vol.103 (8), p.1095-1101
Hauptverfasser:	LUPOGLAZOFF, J. M, DENJOY, I, MAILLARD, G, COUMEL, P, GUICHENEY, P, BERTHET, M, NEYROUD, N, DEMAY, L, RICHARD, P, HAINQUE, B, VAKSMANN, G, KLUG, D, LEENHARDT, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Cardiac dysrhythmias Cardiology and cardiovascular system Cardiology. Vascular system Cation Transport Proteins DNA-Binding Proteins Electrocardiography Electrocardiography, Ambulatory Electrocardiography, Ambulatory - methods ERG1 Potassium Channel Ether-A-Go-Go Potassium Channels Female Heart Human health and pathology Humans KCNQ Potassium Channels KCNQ1 Potassium Channel Life Sciences Long QT Syndrome Long QT Syndrome - genetics Long QT Syndrome - physiopathology Male Medical sciences Mutation Potassium Channels Potassium Channels - genetics Potassium Channels, Voltage-Gated Trans-Activators Transcriptional Regulator ERG
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