Physiological role of endothelin-1 in flow-mediated vasodilatation in humans and impact of cardiovascular risk factors

The current study addressed the hypothesis that the local decrease in endothelin-1 (ET-1) bioavailability during sustained flow increases contributes to endothelium-dependent, flow-mediated dilatation (FMD) of conduit arteries and is altered in presence of cardiovascular risk factors. In nine young...

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Veröffentlicht in:	Journal of hypertension 2017-06, Vol.35 (6), p.1204-1212
Hauptverfasser:	Bellien, Jérémy, Iacob, Michèle, Monteil, Christelle, Rémy-Jouet, Isabelle, Roche, Clothilde, Duflot, Thomas, Vendeville, Cathy, Gutierrez, Laurence, Thuillez, Christian, Richard, Vincent, Joannidès, Robinson
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cardiology and cardiovascular system Cardiovascular Diseases Endothelin A Receptor Antagonists - pharmacology Endothelin B Receptor Antagonists - pharmacology Endothelin Receptor Antagonists - pharmacology Endothelin-1 - physiology Female Hemodynamics - physiology Human health and pathology Humans Life Sciences Male Nitric Oxide - metabolism Oligopeptides - pharmacology Peptides, Cyclic - pharmacology Piperidines - pharmacology Risk Factors Tissues and Organs Vasodilation - drug effects Vasodilation - physiology Young Adult
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