KiSS-1 and GPR54 Genes are Co-Expressed in Rat Gonadotrophs and Differentially Regulated In Vivo by Oestradiol and Gonadotrophin-Releasing Hormone

Kisspeptin, the product derived from KiSS‐1, and its cognate receptor, GPR54, both exert a role in the neuroendocrine control of reproduction by regulating gonadotrophin‐releasing hormone (GnRH) secretion. In the present study, we demonstrate, using dual immunofluorescence with specific antibodies,...

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Veröffentlicht in:	Journal of neuroendocrinology 2008-03, Vol.20 (3), p.381-393
Hauptverfasser:	Richard, N., Galmiche, G., Corvaisier, S., Caraty, A., Kottler, M.-L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Biological and medical sciences Cells, Cultured Estradiol - pharmacology Estradiol - physiology Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects GnRH analog gonadotrophin Gonadotrophs - metabolism Gonadotropin-Releasing Hormone - physiology GPR54 KiSS-1 Kisspeptins Life Sciences Male Molecular biology oestrogen pituitary Pituitary Gland - metabolism Proteins - genetics Proteins - metabolism Rats Rats, Sprague-Dawley Receptors, Estrogen - metabolism Receptors, Estrogen - physiology Receptors, G-Protein-Coupled - genetics Receptors, G-Protein-Coupled - metabolism Receptors, Kisspeptin-1 reproduction Reproductive Biology Vertebrates: endocrinology
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