Allelic inactivation of the pseudoautosomal gene SYBL1 is controlled by epigenetic mechanisms common to the X and Y chromosomes

On the human long-arm pseudoautosomal region (XqPAR), genes that are subject to inactivation are closely linked with those that escape. Genes subject to inactivation are not only silenced on the inactive X in females, but they are also inactivated on the Y chromosome in males. One of the genes subje...

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Veröffentlicht in:	Human molecular genetics 2002-12, Vol.11 (25), p.3191-3198
Hauptverfasser:	Matarazzo, Maria Rosaria, De Bonis, Maria Luigia, Gregory, Richard I., Vacca, Marcella, Hansen, R. Scott, Mercadante, Grazia, D'Urso, Michele, Feil, Robert, D'Esposito, Maurizio
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biochemistry, Molecular Biology Biological and medical sciences Cell Line, Transformed Chromatin - genetics Chromosomes, Human, X - genetics Chromosomes, Human, Y - genetics CpG Islands - genetics DNA Methylation Female Fibroblasts - chemistry Fibroblasts - metabolism Fibroblasts - virology Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - genetics Gene Silencing Genetic Carrier Screening Herpesvirus 4, Human Histones - chemistry Histones - metabolism Humans Hybrid Cells Life Sciences Lymphocytes - chemistry Lymphocytes - metabolism Lymphocytes - virology Male Membrane Proteins - biosynthesis Membrane Proteins - genetics Molecular and cellular biology Molecular genetics Promoter Regions, Genetic - genetics R-SNARE Proteins
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