Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast

Laser speckle contrast imaging (LSCI) is a non-invasive microvascular blood flow assessment technique with good temporal and spatial resolution. Most LSCI systems, including commercial devices, can perform only qualitative blood flow evaluation, which is a major limitation of this technique. There a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Physics in medicine & biology 2017-12, Vol.63 (1), p.015024-015024
Hauptverfasser: Vaz, Pedro G, Humeau-Heurtier, Anne, Figueiras, Edite, Correia, Carlos, Cardoso, João
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 015024
container_issue 1
container_start_page 015024
container_title Physics in medicine & biology
container_volume 63
creator Vaz, Pedro G
Humeau-Heurtier, Anne
Figueiras, Edite
Correia, Carlos
Cardoso, João
description Laser speckle contrast imaging (LSCI) is a non-invasive microvascular blood flow assessment technique with good temporal and spatial resolution. Most LSCI systems, including commercial devices, can perform only qualitative blood flow evaluation, which is a major limitation of this technique. There are several factors that prevent the utilization of LSCI as a quantitative technique. Among these factors, we can highlight the effect of static scatterers. The goal of this work was to study the influence of differences in static and dynamic scatterer concentration on laser speckle correlation and contrast. In order to achieve this, a laser speckle prototype was developed and tested using an optical phantom with various concentrations of static and dynamic scatterers. It was found that the laser speckle correlation could be used to estimate the relative concentration of static/dynamic scatterers within a sample. Moreover, the speckle correlation proved to be independent of the dynamic scatterer velocity, which is a fundamental characteristic to be used in contrast correction.
doi_str_mv 10.1088/1361-6560/aa9f3a
format Article
fullrecord <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_02155893v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1973021747</sourcerecordid><originalsourceid>FETCH-LOGICAL-c478t-58c4c4f46a8321af8b1b0f62dc4207a0c399cbcbbb8b6b354391c566d27b9a583</originalsourceid><addsrcrecordid>eNp1kcFPHCEUh0lTo-vWu6eGY006CsMMA70ZY7XJJl7smTwYsKOzMAXGuP-9bMburSdeXr7fF_J-CJ1TckmJEFeUcVrxlpMrAOkYfEKrw-ozWhHCaCVp256g05SeCaFU1M0xOqllTVrKxQpNt85Zk3FwOGXIg8HJQM422pjw4PEIyUacJmteRotN8DlCynjYwtPgn35g8Ni-TTYOW-szjEUy9zscfEFjtGMxlhl8f4h-QUcOxmTPPt41-v3z9vHmvto83P26ud5UpulErlphGtO4hoNgNQUnNNXE8bo3TU06IIZJabTRWgvNNWsbJqlpOe_rTktoBVuji8X7B0Y1lf9B3KkAg7q_3qj9jtTlMEKyV1rYbws7xfB3timr7ZCMHUfwNsxJUdmxgndNV1CyoCaGlKJ1Bzclat-J2heg9gWopZMS-fphn_XW9ofAvxIK8H0BhjCp5zBHXw7zf9874AGWqQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1973021747</pqid></control><display><type>article</type><title>Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast</title><source>MEDLINE</source><source>IOP Publishing Journals</source><source>Institute of Physics (IOP) Journals - HEAL-Link</source><creator>Vaz, Pedro G ; Humeau-Heurtier, Anne ; Figueiras, Edite ; Correia, Carlos ; Cardoso, João</creator><creatorcontrib>Vaz, Pedro G ; Humeau-Heurtier, Anne ; Figueiras, Edite ; Correia, Carlos ; Cardoso, João</creatorcontrib><description>Laser speckle contrast imaging (LSCI) is a non-invasive microvascular blood flow assessment technique with good temporal and spatial resolution. Most LSCI systems, including commercial devices, can perform only qualitative blood flow evaluation, which is a major limitation of this technique. There are several factors that prevent the utilization of LSCI as a quantitative technique. Among these factors, we can highlight the effect of static scatterers. The goal of this work was to study the influence of differences in static and dynamic scatterer concentration on laser speckle correlation and contrast. In order to achieve this, a laser speckle prototype was developed and tested using an optical phantom with various concentrations of static and dynamic scatterers. It was found that the laser speckle correlation could be used to estimate the relative concentration of static/dynamic scatterers within a sample. Moreover, the speckle correlation proved to be independent of the dynamic scatterer velocity, which is a fundamental characteristic to be used in contrast correction.</description><identifier>ISSN: 0031-9155</identifier><identifier>ISSN: 1361-6560</identifier><identifier>EISSN: 1361-6560</identifier><identifier>DOI: 10.1088/1361-6560/aa9f3a</identifier><identifier>PMID: 29205168</identifier><identifier>CODEN: PHMBA7</identifier><language>eng</language><publisher>England: IOP Publishing</publisher><subject>Algorithms ; Engineering Sciences ; Hemodynamics ; Humans ; Image Interpretation, Computer-Assisted - methods ; laser speckle contrast imaging ; Laser-Doppler Flowmetry - methods ; Phantoms, Imaging ; Signal and Image processing ; spatial contrast ; speckle correlation ; static scatterers</subject><ispartof>Physics in medicine &amp; biology, 2017-12, Vol.63 (1), p.015024-015024</ispartof><rights>2017 Institute of Physics and Engineering in Medicine</rights><rights>Attribution</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c478t-58c4c4f46a8321af8b1b0f62dc4207a0c399cbcbbb8b6b354391c566d27b9a583</citedby><cites>FETCH-LOGICAL-c478t-58c4c4f46a8321af8b1b0f62dc4207a0c399cbcbbb8b6b354391c566d27b9a583</cites><orcidid>0000-0003-3490-7789 ; 0000-0002-6289-0040</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://iopscience.iop.org/article/10.1088/1361-6560/aa9f3a/pdf$$EPDF$$P50$$Giop$$Hfree_for_read</linktopdf><link.rule.ids>230,314,780,784,885,27924,27925,53846,53893</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29205168$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-02155893$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Vaz, Pedro G</creatorcontrib><creatorcontrib>Humeau-Heurtier, Anne</creatorcontrib><creatorcontrib>Figueiras, Edite</creatorcontrib><creatorcontrib>Correia, Carlos</creatorcontrib><creatorcontrib>Cardoso, João</creatorcontrib><title>Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast</title><title>Physics in medicine &amp; biology</title><addtitle>PMB</addtitle><addtitle>Phys. Med. Biol</addtitle><description>Laser speckle contrast imaging (LSCI) is a non-invasive microvascular blood flow assessment technique with good temporal and spatial resolution. Most LSCI systems, including commercial devices, can perform only qualitative blood flow evaluation, which is a major limitation of this technique. There are several factors that prevent the utilization of LSCI as a quantitative technique. Among these factors, we can highlight the effect of static scatterers. The goal of this work was to study the influence of differences in static and dynamic scatterer concentration on laser speckle correlation and contrast. In order to achieve this, a laser speckle prototype was developed and tested using an optical phantom with various concentrations of static and dynamic scatterers. It was found that the laser speckle correlation could be used to estimate the relative concentration of static/dynamic scatterers within a sample. Moreover, the speckle correlation proved to be independent of the dynamic scatterer velocity, which is a fundamental characteristic to be used in contrast correction.</description><subject>Algorithms</subject><subject>Engineering Sciences</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>laser speckle contrast imaging</subject><subject>Laser-Doppler Flowmetry - methods</subject><subject>Phantoms, Imaging</subject><subject>Signal and Image processing</subject><subject>spatial contrast</subject><subject>speckle correlation</subject><subject>static scatterers</subject><issn>0031-9155</issn><issn>1361-6560</issn><issn>1361-6560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>O3W</sourceid><sourceid>EIF</sourceid><recordid>eNp1kcFPHCEUh0lTo-vWu6eGY006CsMMA70ZY7XJJl7smTwYsKOzMAXGuP-9bMburSdeXr7fF_J-CJ1TckmJEFeUcVrxlpMrAOkYfEKrw-ozWhHCaCVp256g05SeCaFU1M0xOqllTVrKxQpNt85Zk3FwOGXIg8HJQM422pjw4PEIyUacJmteRotN8DlCynjYwtPgn35g8Ni-TTYOW-szjEUy9zscfEFjtGMxlhl8f4h-QUcOxmTPPt41-v3z9vHmvto83P26ud5UpulErlphGtO4hoNgNQUnNNXE8bo3TU06IIZJabTRWgvNNWsbJqlpOe_rTktoBVuji8X7B0Y1lf9B3KkAg7q_3qj9jtTlMEKyV1rYbws7xfB3timr7ZCMHUfwNsxJUdmxgndNV1CyoCaGlKJ1Bzclat-J2heg9gWopZMS-fphn_XW9ofAvxIK8H0BhjCp5zBHXw7zf9874AGWqQ</recordid><startdate>20171229</startdate><enddate>20171229</enddate><creator>Vaz, Pedro G</creator><creator>Humeau-Heurtier, Anne</creator><creator>Figueiras, Edite</creator><creator>Correia, Carlos</creator><creator>Cardoso, João</creator><general>IOP Publishing</general><scope>O3W</scope><scope>TSCCA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0003-3490-7789</orcidid><orcidid>https://orcid.org/0000-0002-6289-0040</orcidid></search><sort><creationdate>20171229</creationdate><title>Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast</title><author>Vaz, Pedro G ; Humeau-Heurtier, Anne ; Figueiras, Edite ; Correia, Carlos ; Cardoso, João</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-58c4c4f46a8321af8b1b0f62dc4207a0c399cbcbbb8b6b354391c566d27b9a583</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Algorithms</topic><topic>Engineering Sciences</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted - methods</topic><topic>laser speckle contrast imaging</topic><topic>Laser-Doppler Flowmetry - methods</topic><topic>Phantoms, Imaging</topic><topic>Signal and Image processing</topic><topic>spatial contrast</topic><topic>speckle correlation</topic><topic>static scatterers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vaz, Pedro G</creatorcontrib><creatorcontrib>Humeau-Heurtier, Anne</creatorcontrib><creatorcontrib>Figueiras, Edite</creatorcontrib><creatorcontrib>Correia, Carlos</creatorcontrib><creatorcontrib>Cardoso, João</creatorcontrib><collection>Institute of Physics Open Access Journal Titles</collection><collection>IOPscience (Open Access)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>Physics in medicine &amp; biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vaz, Pedro G</au><au>Humeau-Heurtier, Anne</au><au>Figueiras, Edite</au><au>Correia, Carlos</au><au>Cardoso, João</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast</atitle><jtitle>Physics in medicine &amp; biology</jtitle><stitle>PMB</stitle><addtitle>Phys. Med. Biol</addtitle><date>2017-12-29</date><risdate>2017</risdate><volume>63</volume><issue>1</issue><spage>015024</spage><epage>015024</epage><pages>015024-015024</pages><issn>0031-9155</issn><issn>1361-6560</issn><eissn>1361-6560</eissn><coden>PHMBA7</coden><abstract>Laser speckle contrast imaging (LSCI) is a non-invasive microvascular blood flow assessment technique with good temporal and spatial resolution. Most LSCI systems, including commercial devices, can perform only qualitative blood flow evaluation, which is a major limitation of this technique. There are several factors that prevent the utilization of LSCI as a quantitative technique. Among these factors, we can highlight the effect of static scatterers. The goal of this work was to study the influence of differences in static and dynamic scatterer concentration on laser speckle correlation and contrast. In order to achieve this, a laser speckle prototype was developed and tested using an optical phantom with various concentrations of static and dynamic scatterers. It was found that the laser speckle correlation could be used to estimate the relative concentration of static/dynamic scatterers within a sample. Moreover, the speckle correlation proved to be independent of the dynamic scatterer velocity, which is a fundamental characteristic to be used in contrast correction.</abstract><cop>England</cop><pub>IOP Publishing</pub><pmid>29205168</pmid><doi>10.1088/1361-6560/aa9f3a</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-3490-7789</orcidid><orcidid>https://orcid.org/0000-0002-6289-0040</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0031-9155
ispartof Physics in medicine & biology, 2017-12, Vol.63 (1), p.015024-015024
issn 0031-9155
1361-6560
1361-6560
language eng
recordid cdi_hal_primary_oai_HAL_hal_02155893v1
source MEDLINE; IOP Publishing Journals; Institute of Physics (IOP) Journals - HEAL-Link
subjects Algorithms
Engineering Sciences
Hemodynamics
Humans
Image Interpretation, Computer-Assisted - methods
laser speckle contrast imaging
Laser-Doppler Flowmetry - methods
Phantoms, Imaging
Signal and Image processing
spatial contrast
speckle correlation
static scatterers
title Effect of static scatterers in laser speckle contrast imaging: an experimental study on correlation and contrast
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T08%3A32%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effect%20of%20static%20scatterers%20in%20laser%20speckle%20contrast%20imaging:%20an%20experimental%20study%20on%20correlation%20and%20contrast&rft.jtitle=Physics%20in%20medicine%20&%20biology&rft.au=Vaz,%20Pedro%20G&rft.date=2017-12-29&rft.volume=63&rft.issue=1&rft.spage=015024&rft.epage=015024&rft.pages=015024-015024&rft.issn=0031-9155&rft.eissn=1361-6560&rft.coden=PHMBA7&rft_id=info:doi/10.1088/1361-6560/aa9f3a&rft_dat=%3Cproquest_hal_p%3E1973021747%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1973021747&rft_id=info:pmid/29205168&rfr_iscdi=true