Effects of Pentamidine on Polyamine Level and Biosynthesis in Wild-Type, Pentamidine-Treated, and Pentamidine-ResistantLeishmania

Polyamine biosynthesis was studied in wild-type promastigotes ofLeishmania donovaniandLeishmania amazonensistreated with pentamidine and in the parasites resistant to this drug. Treatment of wild-type clones with low pentamidine concentrations for 24 hr provoked a strong decrease in arginine, ornith...

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Veröffentlicht in:	Experimental parasitology 1997-03, Vol.85 (3), p.274-282
Hauptverfasser:	Basselin, Mireille, Badet-Denisot, Marie-Ange, Lawrence, Françoise, Robert-Gero, Malka
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biochemistry, Molecular Biology Life Sciences Microbiology and Parasitology Molecular biology
Online-Zugang:	Volltext
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