Insights in the rational design of synthetic multivalent glycoconjugates as lectin ligands

Much effort has been made during the last decade to design lectin inhibitors as therapeutics against viral and bacterial adhesion or to control biological functions. The chemical strategy adopted generally consists in the tethering of several binding epitopes on a common scaffold. The resulting mult...

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Veröffentlicht in:	Organic & biomolecular chemistry 2011-01, Vol.9 (4), p.966-979
Hauptverfasser:	Deniaud, David, Julienne, Karine, Gouin, Sébastien G
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemical Sciences Glycoconjugates - chemical synthesis Glycosides - chemistry Lectins - chemistry Ligands Nanoparticles - chemistry Polymers - chemistry
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