Stage-specific expression of the Kit receptor and its ligand (KL) during male gametogenesis in the mouse: a Kit-KL interaction critical for meiosis

The Kit receptor and its ligand KL, which together constitute an essential effector at various stages of embryonic development, are both present during adult gametogenesis. In the testis, KL is expressed in Sertoli cells, and Kit in germ cells, starting at the premeiotic stages. A series of observat...

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Veröffentlicht in:	Development (Cambridge) 1998-11, Vol.125 (22), p.4585-4593
Hauptverfasser:	Vincent, S, Segretain, D, Nishikawa, S, Nishikawa, S I, Sage, J, Cuzin, F, Rassoulzadegan, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biochemistry, Molecular Biology Cell Differentiation Cell Line Coculture Techniques Development Biology Gametogenesis Gene Expression Haploidy Life Sciences Male Meiosis Mice Mice, Inbred Strains Mice, Transgenic Molecular biology Periodicity Protein Binding Proto-Oncogene Proteins c-kit - isolation & purification Sertoli Cells - cytology Spermatocytes - cytology Spermatogenesis Stem Cell Factor - isolation & purification Testis - cytology Tissue Distribution
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