CYP26 function is required for the tissue-specific modulation of retinoic acid signaling during amphioxus development

During development, morphogens, such as retinoic acid (RA), act as mediators of intercellular communication systems to control patterning and cell fate specification processes. In vertebrates, the tightly regulated production and degradation of RA creates an anterior-posterior (A-P) morphogen gradie...

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Veröffentlicht in:	The International journal of developmental biology 2017, Vol.61 (10-11-12), p.733-747
Hauptverfasser:	Carvalho, João E, Lahaye, François, Croce, Jenifer C, Schubert, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning Body Patterning - genetics Central Nervous System Central Nervous System - embryology Central Nervous System - metabolism Cytochrome P450 Family 26 Cytochrome P450 Family 26 - genetics Development Biology Embryo, Nonmammalian Embryo, Nonmammalian - embryology Embryo, Nonmammalian - metabolism Embryology and Organogenesis Gene Expression Regulation, Developmental Gene Expression Regulation, Enzymologic Isoenzymes Isoenzymes - genetics Lancelets Lancelets - embryology Lancelets - enzymology Lancelets - genetics Life Sciences Organ Specificity Organ Specificity - genetics Signal Transduction Tretinoin Tretinoin - metabolism
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