Iron-catalyzed carbonylative alkyl-acylation of heteroarenes

[Display omitted] •Iron-catalyzed intermolecular coupling of acyl radical with heteroarenes.•Generating acyl radicals from cyclobutanone oximes and carbon monoxide.•A broad range of alkyl heteroaryl ketones are synthesized with an excellent functional group tolerance. Herein we present an efficient carbonylative protocol for the introduction of an alkyl-acyl group into heteroarenes from cyclobutanone oximes. In the presence of Fe(OTf)2 catalyst, proceeds via intermolecular alkyl-acylation of different heteroarenes. A broad range of alkyl heteroaryl ketones are synthesized with excellent functional group tolerance with good chemoselectivity.