Improved stability of lipiodol–drug emulsion for transarterial chemoembolisation of hepatocellular carcinoma results in improved pharmacokinetic profile: Proof of concept using idarubicin

Objectives To investigate the relationship between the improved stability of an anticancer drug–lipiodol emulsion and pharmacokinetic (PK) profile for transarterial chemoembolisation (TACE) of hepatocellular carcinoma (HCC). Methods The stability of four doxorubicin– or idarubicin–lipiodol emulsions...

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Veröffentlicht in:	European radiology 2016-02, Vol.26 (2), p.601-609
Hauptverfasser:	Boulin, Mathieu, Schmitt, Antonin, Delhom, Elisabeth, Cercueil, Jean-Pierre, Wendremaire, Maëva, Imbs, Diane-Charlotte, Fohlen, Audrey, Panaro, Fabrizio, Herrero, Astrid, Denys, Alban, Guiu, Boris
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibiotics, Antineoplastic - administration & dosage Antibiotics, Antineoplastic - pharmacokinetics Carcinoma, Hepatocellular - therapy Chemoembolization, Therapeutic - methods Cytotoxicity Diagnostic Radiology Embolization Ethiodized Oil - administration & dosage Experimental Female Humans Idarubicin - administration & dosage Idarubicin - pharmacokinetics Imaging Internal Medicine Interventional Radiology Life Sciences Liver cancer Liver Neoplasms - therapy Male Medicine Medicine & Public Health Neuroradiology Pharmacokinetics Pharmacy Prospective Studies Radiology Treatment Outcome Tumors Ultrasound
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