Impact of a Swiss adverse drug event prevention collaborative
Rationale, aims and objectives The Hospital Federation of Vaud (Switzerland) used a Breakthrough Collaborative with the aim of reducing adverse drug events (ADEs) by 20% in 10 participating hospitals. Methods A set of interventions (covering patient identification, high‐alert medication and medicati...
Gespeichert in:
| Veröffentlicht in: | Journal of evaluation in clinical practice 2015-08, Vol.21 (4), p.717-726 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 726 |
|---|---|
| container_issue | 4 |
| container_start_page | 717 |
| container_title | Journal of evaluation in clinical practice |
| container_volume | 21 |
| creator | Staines, Anthony Mattia, Costanza Schaad, Nicolas Lécureux, Estelle Bonnabry, Pascal |
| description | Rationale, aims and objectives
The Hospital Federation of Vaud (Switzerland) used a Breakthrough Collaborative with the aim of reducing adverse drug events (ADEs) by 20% in 10 participating hospitals.
Methods
A set of interventions (covering patient identification, high‐alert medication and medication preparation in the ward) was deployed over 18 months starting in October 2010. All hospitals monitored discrepancies between drugs prescribed and those prepared for administration, as well as the occurrence of ADEs using the ADE Trigger Tool for 18 months (cohort 1). A subset of five hospitals continued this monitoring for 12 additional months (cohort 2).
Results
In cohort 1, pill box discrepancies were present in 5.9% of doses (n = 9772) in 2011 and in 5.8% (n = 2251) in the first 3 months of 2012 (no statistical significance). There were no significant differences in the rate of ADEs/1000 doses across time (1.2 in 2010, 1.0 in 2011 and 1.0 in 2012). In cohort 2, pill box discrepancies were reduced from 6.5% (n = 4846 doses) in 2011 to 4.4% (n = 7355) in 2012 (P |
| doi_str_mv | 10.1111/jep.12376 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_02021352v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1700335204</sourcerecordid><originalsourceid>FETCH-LOGICAL-h3566-76ef51d7e34a169adc0280b2d36a8d073a712193e4234ca852232924b219a2d23</originalsourceid><addsrcrecordid>eNqNkU9TwjAQxTOOjiB68As4PeqhkGzahB48KIMUhkHHv8dM2gYptrQ2bZFvb6DI2Vx2Z_N7Oy95CF0S3CXm9JYq7xKgnB2hNqHMtYG79Hjbu8wm4DktdKb1EmNCsctPUQsYJoRz3ka34zSXYWllc0taL-tYa0tGtSq0sqKi-rRUrVallRe7GmcrK8ySRAZZIcu4VufoZC4TrS72tYPeHoavA9-ePo7Gg7upvTAOmM2Zmrsk4oo6kjBPRiGGPg4gokz2I8yp5ASIR5UD1All3wWg4IETmKGECGgH3TR7FzIReRGnstiITMbCv5uK7QwDBvNaqIlhrxs2L7LvSulSpLEOlXG9UlmlBeEYmON4jP0HxdRsxY5Br_ZoFaQqOpj4-0kD9BpgHSdqc7gnWGwjEiYisYtITIZPu8Yo7EYR61L9HBSy-BKMU-6Kj9lI-PR58j7z74VHfwEFe46R</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1700335204</pqid></control><display><type>article</type><title>Impact of a Swiss adverse drug event prevention collaborative</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Staines, Anthony ; Mattia, Costanza ; Schaad, Nicolas ; Lécureux, Estelle ; Bonnabry, Pascal</creator><creatorcontrib>Staines, Anthony ; Mattia, Costanza ; Schaad, Nicolas ; Lécureux, Estelle ; Bonnabry, Pascal</creatorcontrib><description>Rationale, aims and objectives
The Hospital Federation of Vaud (Switzerland) used a Breakthrough Collaborative with the aim of reducing adverse drug events (ADEs) by 20% in 10 participating hospitals.
Methods
A set of interventions (covering patient identification, high‐alert medication and medication preparation in the ward) was deployed over 18 months starting in October 2010. All hospitals monitored discrepancies between drugs prescribed and those prepared for administration, as well as the occurrence of ADEs using the ADE Trigger Tool for 18 months (cohort 1). A subset of five hospitals continued this monitoring for 12 additional months (cohort 2).
Results
In cohort 1, pill box discrepancies were present in 5.9% of doses (n = 9772) in 2011 and in 5.8% (n = 2251) in the first 3 months of 2012 (no statistical significance). There were no significant differences in the rate of ADEs/1000 doses across time (1.2 in 2010, 1.0 in 2011 and 1.0 in 2012). In cohort 2, pill box discrepancies were reduced from 6.5% (n = 4846 doses) in 2011 to 4.4% (n = 7355) in 2012 (P < 0.001) to 3.0% for the first 3 months of 2013 (n = 2251; P = 0.004). The rate of ADEs/1000 doses decreased (1.8 in 2010, 1.1 in 2011 and 0.6 in 2012/13 (P = 0.008 for 2010–2011, and P < 0.001 for 2011–2012/2013).
Conclusions
Reductions in drug discrepancies and ADEs occurred in the cohort with the longer monitoring duration. Factors contributing to success may include the strategic status of the project, executive support, perseverance in post‐intervention measurement, and institution‐wide rather than partial deployment.</description><identifier>ISSN: 1356-1294</identifier><identifier>EISSN: 1365-2753</identifier><identifier>DOI: 10.1111/jep.12376</identifier><identifier>PMID: 26011777</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>adverse drug events ; Breakthrough Collaborative ; Business administration ; Cooperative Behavior ; Drug-Related Side Effects and Adverse Reactions - prevention & control ; Health Services Research ; Humanities and Social Sciences ; Humans ; Medication Errors - prevention & control ; medication safety ; Medication Systems, Hospital ; Outcome and Process Assessment (Health Care) ; quality improvement ; Switzerland ; Trigger Tool</subject><ispartof>Journal of evaluation in clinical practice, 2015-08, Vol.21 (4), p.717-726</ispartof><rights>2015 John Wiley & Sons, Ltd.</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fjep.12376$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fjep.12376$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26011777$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.science/hal-02021352$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Staines, Anthony</creatorcontrib><creatorcontrib>Mattia, Costanza</creatorcontrib><creatorcontrib>Schaad, Nicolas</creatorcontrib><creatorcontrib>Lécureux, Estelle</creatorcontrib><creatorcontrib>Bonnabry, Pascal</creatorcontrib><title>Impact of a Swiss adverse drug event prevention collaborative</title><title>Journal of evaluation in clinical practice</title><addtitle>J Eval Clin Pract</addtitle><description>Rationale, aims and objectives
The Hospital Federation of Vaud (Switzerland) used a Breakthrough Collaborative with the aim of reducing adverse drug events (ADEs) by 20% in 10 participating hospitals.
Methods
A set of interventions (covering patient identification, high‐alert medication and medication preparation in the ward) was deployed over 18 months starting in October 2010. All hospitals monitored discrepancies between drugs prescribed and those prepared for administration, as well as the occurrence of ADEs using the ADE Trigger Tool for 18 months (cohort 1). A subset of five hospitals continued this monitoring for 12 additional months (cohort 2).
Results
In cohort 1, pill box discrepancies were present in 5.9% of doses (n = 9772) in 2011 and in 5.8% (n = 2251) in the first 3 months of 2012 (no statistical significance). There were no significant differences in the rate of ADEs/1000 doses across time (1.2 in 2010, 1.0 in 2011 and 1.0 in 2012). In cohort 2, pill box discrepancies were reduced from 6.5% (n = 4846 doses) in 2011 to 4.4% (n = 7355) in 2012 (P < 0.001) to 3.0% for the first 3 months of 2013 (n = 2251; P = 0.004). The rate of ADEs/1000 doses decreased (1.8 in 2010, 1.1 in 2011 and 0.6 in 2012/13 (P = 0.008 for 2010–2011, and P < 0.001 for 2011–2012/2013).
Conclusions
Reductions in drug discrepancies and ADEs occurred in the cohort with the longer monitoring duration. Factors contributing to success may include the strategic status of the project, executive support, perseverance in post‐intervention measurement, and institution‐wide rather than partial deployment.</description><subject>adverse drug events</subject><subject>Breakthrough Collaborative</subject><subject>Business administration</subject><subject>Cooperative Behavior</subject><subject>Drug-Related Side Effects and Adverse Reactions - prevention & control</subject><subject>Health Services Research</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Medication Errors - prevention & control</subject><subject>medication safety</subject><subject>Medication Systems, Hospital</subject><subject>Outcome and Process Assessment (Health Care)</subject><subject>quality improvement</subject><subject>Switzerland</subject><subject>Trigger Tool</subject><issn>1356-1294</issn><issn>1365-2753</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9TwjAQxTOOjiB68As4PeqhkGzahB48KIMUhkHHv8dM2gYptrQ2bZFvb6DI2Vx2Z_N7Oy95CF0S3CXm9JYq7xKgnB2hNqHMtYG79Hjbu8wm4DktdKb1EmNCsctPUQsYJoRz3ka34zSXYWllc0taL-tYa0tGtSq0sqKi-rRUrVallRe7GmcrK8ySRAZZIcu4VufoZC4TrS72tYPeHoavA9-ePo7Gg7upvTAOmM2Zmrsk4oo6kjBPRiGGPg4gokz2I8yp5ASIR5UD1All3wWg4IETmKGECGgH3TR7FzIReRGnstiITMbCv5uK7QwDBvNaqIlhrxs2L7LvSulSpLEOlXG9UlmlBeEYmON4jP0HxdRsxY5Br_ZoFaQqOpj4-0kD9BpgHSdqc7gnWGwjEiYisYtITIZPu8Yo7EYR61L9HBSy-BKMU-6Kj9lI-PR58j7z74VHfwEFe46R</recordid><startdate>201508</startdate><enddate>201508</enddate><creator>Staines, Anthony</creator><creator>Mattia, Costanza</creator><creator>Schaad, Nicolas</creator><creator>Lécureux, Estelle</creator><creator>Bonnabry, Pascal</creator><general>Blackwell Publishing Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>1XC</scope><scope>BXJBU</scope></search><sort><creationdate>201508</creationdate><title>Impact of a Swiss adverse drug event prevention collaborative</title><author>Staines, Anthony ; Mattia, Costanza ; Schaad, Nicolas ; Lécureux, Estelle ; Bonnabry, Pascal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h3566-76ef51d7e34a169adc0280b2d36a8d073a712193e4234ca852232924b219a2d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>adverse drug events</topic><topic>Breakthrough Collaborative</topic><topic>Business administration</topic><topic>Cooperative Behavior</topic><topic>Drug-Related Side Effects and Adverse Reactions - prevention & control</topic><topic>Health Services Research</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Medication Errors - prevention & control</topic><topic>medication safety</topic><topic>Medication Systems, Hospital</topic><topic>Outcome and Process Assessment (Health Care)</topic><topic>quality improvement</topic><topic>Switzerland</topic><topic>Trigger Tool</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Staines, Anthony</creatorcontrib><creatorcontrib>Mattia, Costanza</creatorcontrib><creatorcontrib>Schaad, Nicolas</creatorcontrib><creatorcontrib>Lécureux, Estelle</creatorcontrib><creatorcontrib>Bonnabry, Pascal</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>HAL-SHS: Archive ouverte en Sciences de l'Homme et de la Société</collection><jtitle>Journal of evaluation in clinical practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Staines, Anthony</au><au>Mattia, Costanza</au><au>Schaad, Nicolas</au><au>Lécureux, Estelle</au><au>Bonnabry, Pascal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of a Swiss adverse drug event prevention collaborative</atitle><jtitle>Journal of evaluation in clinical practice</jtitle><addtitle>J Eval Clin Pract</addtitle><date>2015-08</date><risdate>2015</risdate><volume>21</volume><issue>4</issue><spage>717</spage><epage>726</epage><pages>717-726</pages><issn>1356-1294</issn><eissn>1365-2753</eissn><abstract>Rationale, aims and objectives
The Hospital Federation of Vaud (Switzerland) used a Breakthrough Collaborative with the aim of reducing adverse drug events (ADEs) by 20% in 10 participating hospitals.
Methods
A set of interventions (covering patient identification, high‐alert medication and medication preparation in the ward) was deployed over 18 months starting in October 2010. All hospitals monitored discrepancies between drugs prescribed and those prepared for administration, as well as the occurrence of ADEs using the ADE Trigger Tool for 18 months (cohort 1). A subset of five hospitals continued this monitoring for 12 additional months (cohort 2).
Results
In cohort 1, pill box discrepancies were present in 5.9% of doses (n = 9772) in 2011 and in 5.8% (n = 2251) in the first 3 months of 2012 (no statistical significance). There were no significant differences in the rate of ADEs/1000 doses across time (1.2 in 2010, 1.0 in 2011 and 1.0 in 2012). In cohort 2, pill box discrepancies were reduced from 6.5% (n = 4846 doses) in 2011 to 4.4% (n = 7355) in 2012 (P < 0.001) to 3.0% for the first 3 months of 2013 (n = 2251; P = 0.004). The rate of ADEs/1000 doses decreased (1.8 in 2010, 1.1 in 2011 and 0.6 in 2012/13 (P = 0.008 for 2010–2011, and P < 0.001 for 2011–2012/2013).
Conclusions
Reductions in drug discrepancies and ADEs occurred in the cohort with the longer monitoring duration. Factors contributing to success may include the strategic status of the project, executive support, perseverance in post‐intervention measurement, and institution‐wide rather than partial deployment.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26011777</pmid><doi>10.1111/jep.12376</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1356-1294 |
| ispartof | Journal of evaluation in clinical practice, 2015-08, Vol.21 (4), p.717-726 |
| issn | 1356-1294 1365-2753 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_02021352v1 |
| source | MEDLINE; Wiley Online Library All Journals |
| subjects | adverse drug events Breakthrough Collaborative Business administration Cooperative Behavior Drug-Related Side Effects and Adverse Reactions - prevention & control Health Services Research Humanities and Social Sciences Humans Medication Errors - prevention & control medication safety Medication Systems, Hospital Outcome and Process Assessment (Health Care) quality improvement Switzerland Trigger Tool |
| title | Impact of a Swiss adverse drug event prevention collaborative |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T04%3A42%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20a%20Swiss%20adverse%20drug%20event%20prevention%20collaborative&rft.jtitle=Journal%20of%20evaluation%20in%20clinical%20practice&rft.au=Staines,%20Anthony&rft.date=2015-08&rft.volume=21&rft.issue=4&rft.spage=717&rft.epage=726&rft.pages=717-726&rft.issn=1356-1294&rft.eissn=1365-2753&rft_id=info:doi/10.1111/jep.12376&rft_dat=%3Cproquest_hal_p%3E1700335204%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1700335204&rft_id=info:pmid/26011777&rfr_iscdi=true |