T-box genes and retinoic acid signaling regulate the segregation of arterial and venous pole progenitor cells in the murine second heart field

Abstract The arterial and venous poles of the mammalian heart are hotspots of congenital heart defects (CHD) such as those observed in 22q11.2 deletion (or DiGeorge) and Holt-Oram syndromes. These regions of the heart are derived from late differentiating cardiac progenitor cells of the Second Heart...

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Veröffentlicht in:	Human molecular genetics 2018-11, Vol.27 (21), p.3747-3760
Hauptverfasser:	De Bono, Christopher, Thellier, Charlotte, Bertrand, Nicolas, Sturny, Rachel, Jullian, Estelle, Cortes, Claudio, Stefanovic, Sonia, Zaffran, Stéphane, Théveniau-Ruissy, Magali, Kelly, Robert G
Format:	Artikel
Sprache:	eng
Schlagworte:	Life Sciences
Online-Zugang:	Volltext
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