Phenotypic analysis of HIV-1 E157Q integrase polymorphism and impact on virological outcome in patients initiating an integrase inhibitor-based regimen

To assess the phenotypic susceptibility of the E157Q polymorphism in HIV-1 integrase (IN) and the virological outcome of patients infected with E157Q-mutated virus initiating an IN inhibitor (INI)-based regimen. This was a multicentre study assessing IN sequences from INI-naive patients among 17 Fre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of antimicrobial chemotherapy 2018-04, Vol.73 (4), p.1039-1044
Hauptverfasser:	Charpentier, Charlotte, Malet, Isabelle, Andre-Garnier, Elisabeth, Storto, Alexandre, Bocket, Laurence, Amiel, Corinne, Morand-Joubert, Laurence, Tumiotto, Camille, Nguyen, Thuy, Maillard, Anne, Rodallec, Audrey, Leoz, Marie, Montes, Brigitte, Schneider, Véronique, Plantier, Jean-Christophe, Dina, Julia, Pallier, Coralie, Mirand, Audrey, Roussel, Catherine, Signori-Schmuck, Anne, Raymond, Stéphanie, Calvez, Vincent, Delaugerre, Constance, Marcelin, Anne-Geneviève, Descamps, Diane
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteriology France Gene Frequency Genotype HIV Infections - drug therapy HIV Infections - virology HIV Integrase - genetics HIV Integrase Inhibitors - administration & dosage HIV-1 - genetics HIV-1 - isolation & purification Humans Life Sciences Microbiology and Parasitology Mutation, Missense Prevalence Protistology Treatment Outcome Viral Load Virology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!