Comparison of acceptability, skin tolerance, and compliance between handwashing and alcohol-based handrub in ICUs: results of a multicentric study

Objective We compared handwashing (HW) and alcohol-based handrub (ABH) for skin tolerance, acceptability, and hand hygiene compliance in health-care workers (HCWs) in a multicentric study. Design and setting Before/after study over two periods (P1 and P2) in seven ICUs. Monitoring of methicillin-resistant Staphylococcus aureus (MRSA) acquisition in two ICUs (U4 and U6). Subjects and patients All HCWs of the seven ICUs, and the patients of U4 and U6 without MRSA carriage on admission. Interventions Handwashing was available in P1 and P2. ABH was introduced after P1 and available throughout P2. HCWs completed questionnaires on skin tolerance in P1 and P2, and on acceptability in P2. Compliance with hand hygiene was assessed in P1 and P2 using a standardized method. ICU-acquired MRSA colonization/infection in U4 and U6 was recorded. Measurements and main results Hand erythema was reported during P1 and P2 by 21.7 and 11% of HCWs, respectively ( P = 0.01), itching by 15.8 and 7.1% ( P = 0.02), oozing by 0.8 and 1.1% ( P = 0.82), and bleeding by 4.2 and 1.1% ( P = 0.1). ABH was considered easier and quicker than HW ( P