Novel severe wheezy young children phenotypes: Boys atopic multiple-trigger and girls nonatopic uncontrolled wheeze

Background Recurrent wheezing during infancy is a heterogeneous disorder that has been associated with early-onset asthma. Objective To identify phenotypes of severe recurrent wheezing and therapeutic approaches. Methods We performed cluster analysis with 20 variables of 551 children with active ast...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2012-07, Vol.130 (1), p.103-110.e8
Hauptverfasser:	Just, Jocelyne, PhD, MD, Gouvis-Echraghi, Rahele, MD, Couderc, Remy, PhD, PharmD, Guillemot-Lambert, Nathalie, MD, Saint-Pierre, Philippe, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Age Age of Onset Allergies allergy Allergy and Immunology Anti-Asthmatic Agents - therapeutic use Asthma - drug therapy Asthma - etiology Asthma - physiopathology Automation Babies Biological and medical sciences Body mass index Child, Preschool Children & youth Chronic obstructive pulmonary disease, asthma Cluster Analysis Female Food allergies Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Hypersensitivity, Immediate - etiology Hypersensitivity, Immediate - physiopathology ICS Immunoglobulin E - blood Immunopathology Infant Life Sciences Male Medical sciences Phenotype Pneumology preschool children Respiratory Sounds - physiopathology Risk Factors Santé publique et épidémiologie Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Severity of Illness Index Statistical methods Tobacco smoke
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