Line-field confocal time-domain optical coherence tomography with dynamic focusing

Line-field confocal time-domain optical coherence tomography with dynamic focusing

A time-domain optical coherence tomography technique is introduced for high-resolution B-scan imaging in real-time. The technique is based on a two-beam interference microscope with line illumination and line detection using a broadband spatially coherent light source and a line-scan camera. Multipl...

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Veröffentlicht in:Optics express 2018-12, Vol.26 (26), p.33534-33542
Hauptverfasser: Dubois, Arnaud, Levecq, Olivier, Azimani, Hicham, Davis, Arthur, Ogien, Jonas, Siret, David, Barut, Anaïs
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container_end_page 33542
container_issue 26
container_start_page 33534
container_title Optics express
container_volume 26
creator Dubois, Arnaud
Levecq, Olivier
Azimani, Hicham
Davis, Arthur
Ogien, Jonas
Siret, David
Barut, Anaïs
description A time-domain optical coherence tomography technique is introduced for high-resolution B-scan imaging in real-time. The technique is based on a two-beam interference microscope with line illumination and line detection using a broadband spatially coherent light source and a line-scan camera. Multiple (2048) A-scans are acquired in parallel by scanning the sample depth while adjusting the focus. Quasi-isotropic spatial resolution of 1.3 µm × 1.1 µm (lateral × axial) is achieved. In vivo cellular-level resolution imaging of human skin is demonstrated at 10 frames per second with a penetration depth of ∼500 µm.
doi_str_mv 10.1364/OE.26.033534
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subjects Optics
Physics
title Line-field confocal time-domain optical coherence tomography with dynamic focusing
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