New tricks for an old dog: A repurposing approach of apomorphine

Apomorphine is a 150-year old nonspecific dopaminergic agonist, currently indicated for treating motor fluctuations in Parkinson’s disease. At the era of drug repurposing, its pleiotropic biological functions suggest other possible uses. To further explore new therapeutic and diagnostic applications...

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Veröffentlicht in:	European journal of pharmacology 2019-01, Vol.843, p.66-79
Hauptverfasser:	Auffret, Manon, Drapier, Sophie, Vérin, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apomorphine Apomorphine - pharmacology Apomorphine - therapeutic use Cancer Dopamine Agonists - pharmacology Dopamine Agonists - therapeutic use Drug Repositioning Human health and pathology Humans Life Sciences Neoplasms - drug therapy Nervous System Diseases - drug therapy Neurodegenerative diseases Neuroleptic malignant syndrome Pharmaceutical sciences Pharmacology Psychiatrics and mental health Repurposing Sexual disorders Sexual Dysfunction, Physiological - drug therapy
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