Regulation of Corneal Keratin-12 Gene Expression by the Human Kruppel-like Transcription Factor 6

The keratin-12 (K12) protein is essential for the integrity of the corneal epithelium. This study was conducted to investigate the possible involvement of Krüppel-like factor 6 (KLF6) in the corneal regulation of K12 gene expression, in view of the presence of one KLF6 potential binding site in the...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2002-11, Vol.43 (11), p.3422-3429
Hauptverfasser:	Chiambaretta, Frederic, Blanchon, Loic, Rabier, Benedicte, Kao, Winston W.-Y, Liu, Janice J, Dastugue, Bernard, Rigal, Daniele, Sapin, Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Blotting, Western Cell Line Cornea - metabolism Electrophoretic Mobility Shift Assay Epithelial Cells - metabolism Eye and associated structures. Visual pathways and centers. Vision Fluorescent Antibody Technique, Indirect Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Human health and pathology Humans Keratins - genetics Kruppel-Like Factor 6 Kruppel-Like Transcription Factors Life Sciences Molecular Sequence Data Proto-Oncogene Proteins Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Sensory Organs Sequence Analysis, DNA Trans-Activators - physiology Transfection Vertebrates: nervous system and sense organs
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