Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6)

Purpose A pathologic complete response (pCR; ypT0N0) of a rectal tumor after neoadjuvant radiochemotherapy (RCT) is associated with an excellent prognosis. Several retrospective studies have investigated the effect of increasing the delay after RCT. The aim of this study was to evaluate the effect o...

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Veröffentlicht in:	Journal of clinical oncology 2016-11, Vol.34 (31), p.3773-3780
Hauptverfasser:	Lefevre, Jérémie H, Mineur, Laurent, Kotti, Salma, Rullier, Eric, Rouanet, Philippe, de Chaisemartin, Cécile, Meunier, Bernard, Mehrdad, Jafari, Cotte, Eddy, Desrame, Jérome, Karoui, Mehdi, Benoist, Stéphane, Kirzin, Sylvain, Berger, Anne, Panis, Yves, Piessen, Guillaume, Saudemont, Alain, Prudhomme, Michel, Peschaud, Frédérique, Dubois, Anne, Loriau, Jérome, Tuech, Jean-Jacques, Meurette, Guillaume, Lupinacci, Renato, Goasgen, Nicolas, Parc, Yann, Simon, Tabassome, Tiret, Emmanuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer Capecitabine - administration & dosage Chemoradiotherapy Disease-Free Survival Female Fluorouracil - administration & dosage Humans Life Sciences Male Middle Aged Neoadjuvant Therapy Radiotherapy Dosage Rectal Neoplasms - surgery Rectal Neoplasms - therapy Remission Induction Time Factors Treatment Outcome
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