Step-down strategy of spacing TNF-blocker injections for established rheumatoid arthritis in remission: results of the multicentre non-inferiority randomised open-label controlled trial (STRASS: Spacing of TNF-blocker injections in Rheumatoid ArthritiS Study)

Tumour necrosis factor (TNF)-blocker tapering has been proposed for patients with rheumatoid arthritis (RA) in remission.ObjectiveThe trial aims to compare the effect of progressive spacing of TNF-blocker injections (S-arm) to their maintenance (M-arm) for established patients with RA in remission.M...

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Veröffentlicht in:	Annals of the rheumatic diseases 2016-01, Vol.75 (1), p.59-67
Hauptverfasser:	Fautrel, Bruno, Pham, Thao, Alfaiate, Toni, Gandjbakhch, Frédérique, Foltz, Violaine, Morel, Jacques, Dernis, Emmanuelle, Gaudin, Philippe, Brocq, Olivier, Solau-Gervais, Elisabeth, Berthelot, Jean-Marie, Balblanc, Jean-Charles, Mariette, Xavier, Tubach, Florence
Format:	Artikel
Sprache:	eng
Schlagworte:	Adalimumab - administration & dosage Adalimumab - adverse effects Adult Aged Antirheumatic Agents - administration & dosage Antirheumatic Agents - adverse effects Arthritis, Rheumatoid - diagnostic imaging Arthritis, Rheumatoid - drug therapy Biological products Drug Administration Schedule Etanercept - administration & dosage Etanercept - adverse effects Female French language Human health and pathology Humans Informed consent Life Sciences Maintenance Chemotherapy - methods Male Middle Aged Patients Radiography Recurrence Remission (Medicine) Rheumatoid arthritis Rheumatology Rhumatology and musculoskeletal system Severity of Illness Index TNF inhibitors Treatment Outcome Tumor Necrosis Factor-alpha - antagonists & inhibitors Tumor necrosis factor-TNF
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