A phase III study evaluating oral glutamine and transforming growth factor-beta 2 on chemotherapy-induced toxicity in patients with digestive neoplasm

Abstract Background Patients with gastrointestinal (GI) cancer are exposed to cachexia, which is highly correlated with chemotherapy-induced side effects. Research suggests that specific immunonutrients could prevent such toxicities. Aims The primary objective of this phase III study was to evaluate...

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Veröffentlicht in:	Digestive and liver disease 2016-03, Vol.48 (3), p.327-332
Hauptverfasser:	Khemissa, Faïza, Mineur, Laurent, Amsellem, Caroline, Assenat, Eric, Ramdani, Mohamed, Bachmann, Patrick, Janiszewski, Chloé, Cristiani, Isabelle, Collin, Fideline, Courraud, Julie, de Forges, Hélène, Dechelotte, Pierre, Senesse, Pierre
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Cachexia - complications Chemotherapy Dietary Supplements Double-Blind Method Female Fluorouracil - administration & dosage Gastroenterology and Hepatology Gastrointestinal cancer Gastrointestinal Diseases - chemically induced Gastrointestinal Diseases - prevention & control Gastrointestinal Neoplasms - complications Gastrointestinal Neoplasms - drug therapy Glutamine - therapeutic use Human health and pathology Humans Hépatology and Gastroenterology Immunonutrition Life Sciences Male Middle Aged Platinum Compounds - administration & dosage Side effects Transforming Growth Factor beta - therapeutic use
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