A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease

A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease

von Willebrand disease (VWD) is a genetic bleeding disease due to a defect of von Willebrand factor (VWF), a glycoprotein crucial for platelet adhesion to the subendothelium after vascular injury. VWD include quantitative defects of VWF, either partial (type 1 with VWF levels 

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Veröffentlicht in:Medicine (Baltimore) 2016-03, Vol.95 (11)
Hauptverfasser: Veyradier, Agnès, Boisseau, Pierre, Fressinaud, Edith, Caron, Claudine, Ternisien, Catherine, Giraud, Mathilde, Zawadzki, Christophe, Trossaërt, Marc, Itzhar-Baikian, Nathalie, Dreyfus, Marie, d'Oiron, Roseline, Borel-Derlon, Annie, Susen, Sophie, Bézieau, Stéphane, Denis, Cecile, Goudemand, Jenny, von Willebrand Disease, French Reference Center For, Gris, Jean-Christophe
Format: Artikel
Sprache:eng
Schlagworte:
Human health and pathology
Life Sciences
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Zusammenfassung:von Willebrand disease (VWD) is a genetic bleeding disease due to a defect of von Willebrand factor (VWF), a glycoprotein crucial for platelet adhesion to the subendothelium after vascular injury. VWD include quantitative defects of VWF, either partial (type 1 with VWF levels 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000003038