Genetic basis for mycophenolic acid production and strain-dependent production variability in Penicillium roqueforti

Mycophenolic acid (MPA) is a secondary metabolite produced by various Penicillium species including Penicillium roqueforti. The MPA biosynthetic pathway was recently described in Penicillium brevicompactum. In this study, an in silico analysis of the P. roqueforti FM164 genome sequence localized a 2...

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Veröffentlicht in:	Food microbiology 2017-04, Vol.62, p.239-250
Hauptverfasser:	Gillot, Guillaume, Jany, Jean-Luc, Dominguez-Santos, Rebeca, Poirier, Elisabeth, Debaets, Stella, Hidalgo, Pedro I., Ullán, Ricardo V., Coton, Emmanuel, Coton, Monika
Format:	Artikel
Sprache:	eng
Schlagworte:	Cheese - microbiology Computer Simulation Gene Expression Gene Silencing Genes, Fungal Genome, Fungal Life Sciences Microbiology and Parasitology Multigene Family Mycology Mycophenolic acid Mycophenolic Acid - metabolism Mycotoxins Penicillium Penicillium - genetics Penicillium - metabolism Penicillium brevicompactum Penicillium roqueforti Polyketide Synthases - genetics Polyketide Synthases - metabolism Polymerase Chain Reaction Protein Biosynthesis
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