Involvement of GFA1, which encodes glutamine–fructose‐6‐phosphate amidotransferase, in the activation of the chitin synthesis pathway in response to cell‐wall defects in Saccharomyces cerevisiae

Cell‐wall damage caused by mutations of cell‐wall‐related genes triggers a compensatory mechanism which eventually results in hyperaccumulation of chitin reaching 20% of the cell‐wall dry mass. We show that activation of chitin synthesis is accompanied by a rise, from 1.3‐fold to 3.5‐fold according...

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