The systemic nature of CKD

Key Points CKD is an inherently systemic disease Energy balance, innate immunity and neuroendocrine control of organ function are highly integrated biological processes; such integration is disrupted by loss of kidney function, which generates a high risk clinical phenotype The clinical profile of c...

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Veröffentlicht in:	Nature reviews. Nephrology 2017-06, Vol.13 (6), p.344-358
Hauptverfasser:	Zoccali, Carmine, Vanholder, Raymond, Massy, Ziad A., Ortiz, Alberto, Sarafidis, Pantelis, Dekker, Friedo W., Fliser, Danilo, Fouque, Denis, Heine, Gunnar H., Jager, Kitty J., Kanbay, Mehmet, Mallamaci, Francesca, Parati, Gianfranco, Rossignol, Patrick, Wiecek, Andrzej, London, Gerard
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4022/1585/104 692/698/1543/1565 692/699/1670/316 692/699/75 Amino acids Animals Biomarkers Bone Diseases - etiology Care and treatment Chronic kidney failure Development and progression Diagnosis Energy Energy Metabolism Energy storage Epidemiology Glucose Heart Diseases - etiology Hemodialysis Homeostasis Hormones Hospitals Humans Hypertension Immune system Immunity Immunity (Disease) Inflammation Inflammation - etiology Insulin resistance Internal medicine Kidney diseases Life Sciences Lung Diseases - etiology Medicine Medicine & Public Health Metabolic Diseases - etiology Metabolism Nephrology Nervous System Diseases - etiology Pathophysiology Renal Insufficiency, Chronic - complications Renal Insufficiency, Chronic - immunology Renal Insufficiency, Chronic - metabolism review-article Systemic diseases Transplants & implants
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