Influenza viruses production: Evaluation of a novel avian cell line DuckCelt®-T17

Abstract The influenza vaccine manufacturing industry is looking for production cell lines that are easily scalable, highly permissive to multiple viruses, and more effective in term of viral productivity. One critical characteristic of such cell lines is their ability to grow in suspension, in seru...

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Veröffentlicht in:	Vaccine 2018-05, Vol.36 (22), p.3101-3111
Hauptverfasser:	Petiot, Emma, Proust, Anaïs, Traversier, Aurélien, Durous, Laurent, Dappozze, Frédéric, Gras, Marianne, Guillard, Chantal, Balloul, Jean-Marc, Rosa-Calatrava, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Aquatic birds Avian cell line Bioreactors Biotechnology Catalysis Cell Culture Techniques - methods Cell density Cell Line Cell lines Chemical Sciences Developmental stages Ducks Environment and Society Environmental Sciences Epidemics Industrial production Influenza Influenza A Virus, H1N1 Subtype - growth & development Influenza A Virus, H1N1 Subtype - physiology Influenza A Virus, H3N2 Subtype - growth & development Influenza A Virus, H3N2 Subtype - physiology Influenza A Virus, H3N8 Subtype - growth & development Influenza A Virus, H3N8 Subtype - physiology Influenza A Virus, H5N2 Subtype - growth & development Influenza A Virus, H5N2 Subtype - physiology Influenza A Virus, H7N1 Subtype - growth & development Influenza A Virus, H7N1 Subtype - physiology Influenza vaccine Influenza Vaccines Influenza virus strains Kinetics Manufacturing Manufacturing industry Optimization Orthomyxoviridae Orthomyxoviridae - growth & development Orthomyxoviridae - physiology Outbreaks Pandemics Production process optimization Productivity Reaction kinetics RNA-directed DNA polymerase Seeds Strains (organisms) Telomerase Telomerase reverse transcriptase Trypsin Vaccines Virus Cultivation - methods Virus Replication Viruses
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