Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions
Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. However, improved osseointegration is needed as higher marginal bone loss was sometimes reported. In...
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| Veröffentlicht in: | Journal of the European Ceramic Society 2018-03, Vol.38 (3), p.939-948 |
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| container_title | Journal of the European Ceramic Society |
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| creator | Stanciuc, Ana-Maria Flamant, Quentin Sprecher, Christoph Martin Alini, Mauro Anglada, Marc Peroglio, Marianna |
| description | Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. However, improved osseointegration is needed as higher marginal bone loss was sometimes reported. In the present work, 3Y-TZP multi-patterned samples for rapid screening of cell-surface interactions were fabricated by femtosecond laser micromachining. Pits with well-defined edges and micrometric precision in pit diameter, depth and spacing were produced, as determined by white light interferometry. Pits showed a nanometric granular texture on the sidewalls and ripples at pit bottom, as attested by scanning electron microscopy. Focused ion beam analyses indicated limited laser-induced damage. Micropatterns impacted human mesenchymal stem cell (hMSC) size and morphology. Cell area and aspect ratio were mainly influenced by pit diameter, while solidity and circularity were affected by both pit diameter and depth. The pattern 30μm diameter/10μm depth induced the strongest osteoblastic hMSC commitment. |
| doi_str_mv | 10.1016/j.jeurceramsoc.2017.08.019 |
| format | Article |
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The pattern 30μm diameter/10μm depth induced the strongest osteoblastic hMSC commitment.</description><identifier>ISSN: 0955-2219</identifier><identifier>EISSN: 1873-619X</identifier><identifier>DOI: 10.1016/j.jeurceramsoc.2017.08.019</identifier><language>eng</language><publisher>Elsevier Ltd</publisher><subject>Cell culture ; Cell membranes ; Engineering Sciences ; Enginyeria dels materials ; Human Mesenchymal Stem Cells ; Laser ; Materials ; Membranes cel·lulars ; Pattern ; Surface ; Topography ; Zirconi ; Zirconia ; Zirconium ; Àrees temàtiques de la UPC</subject><ispartof>Journal of the European Ceramic Society, 2018-03, Vol.38 (3), p.939-948</ispartof><rights>2017 Elsevier Ltd</rights><rights>info:eu-repo/semantics/openAccess</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c466t-8a32ee3e629607f81608b3fd6b488e3b866b65a1b01d828d5f5fda27ef1ce29a3</citedby><cites>FETCH-LOGICAL-c466t-8a32ee3e629607f81608b3fd6b488e3b866b65a1b01d828d5f5fda27ef1ce29a3</cites><orcidid>0000-0001-6736-6451 ; 0000-0002-5458-3446</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jeurceramsoc.2017.08.019$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,26974,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://hal.science/hal-01814019$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Stanciuc, Ana-Maria</creatorcontrib><creatorcontrib>Flamant, Quentin</creatorcontrib><creatorcontrib>Sprecher, Christoph Martin</creatorcontrib><creatorcontrib>Alini, Mauro</creatorcontrib><creatorcontrib>Anglada, Marc</creatorcontrib><creatorcontrib>Peroglio, Marianna</creatorcontrib><title>Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions</title><title>Journal of the European Ceramic Society</title><description>Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. 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The pattern 30μm diameter/10μm depth induced the strongest osteoblastic hMSC commitment.</description><subject>Cell culture</subject><subject>Cell membranes</subject><subject>Engineering Sciences</subject><subject>Enginyeria dels materials</subject><subject>Human Mesenchymal Stem Cells</subject><subject>Laser</subject><subject>Materials</subject><subject>Membranes cel·lulars</subject><subject>Pattern</subject><subject>Surface</subject><subject>Topography</subject><subject>Zirconi</subject><subject>Zirconia</subject><subject>Zirconium</subject><subject>Àrees temàtiques de la UPC</subject><issn>0955-2219</issn><issn>1873-619X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>XX2</sourceid><recordid>eNqNkU9LJDEQxcOisKPud2i8eejeqvR0OvEm_lmFAS8K7imk05XdDD0dSXoE_fSmHRWPHkJI5f3qwXuMHSNUCCh-r6s1baOlaDYp2IoDthXIClD9YAuUbV0KVA97bAGqaUrOUf1kBymtIQtBqQX7e0WbKSSyYeyLwSSKxWY7TL58NNNEcfTjvyK44sXHrPCmcCEWyUaijx9Lw1CmbXTGUuHHzBg7-TCmI7bvzJDo1_t9yO6vLu_Or8vV7Z-b87NVaZdCTKU0NSeqSXAloHUSBciudr3ollJS3UkhOtEY7AB7yWXfuMb1hrfk0BJXpj5kJ7u9_82gH6PfmPisg_H6-myl5xmgxGVO5AmzFndam7ZWR8rBWTO9qT8f8-HQcl0DlzAzp-9MDClFcp8mCHouQa_11xL0XIIGmX1Vhi92MOUEnjxFnayn0VLvs-Gk--C_s-YVhdWYxg</recordid><startdate>201803</startdate><enddate>201803</enddate><creator>Stanciuc, Ana-Maria</creator><creator>Flamant, Quentin</creator><creator>Sprecher, Christoph Martin</creator><creator>Alini, Mauro</creator><creator>Anglada, Marc</creator><creator>Peroglio, Marianna</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>AAYXX</scope><scope>CITATION</scope><scope>XX2</scope><scope>1XC</scope><orcidid>https://orcid.org/0000-0001-6736-6451</orcidid><orcidid>https://orcid.org/0000-0002-5458-3446</orcidid></search><sort><creationdate>201803</creationdate><title>Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions</title><author>Stanciuc, Ana-Maria ; Flamant, Quentin ; Sprecher, Christoph Martin ; Alini, Mauro ; Anglada, Marc ; Peroglio, Marianna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c466t-8a32ee3e629607f81608b3fd6b488e3b866b65a1b01d828d5f5fda27ef1ce29a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Cell culture</topic><topic>Cell membranes</topic><topic>Engineering Sciences</topic><topic>Enginyeria dels materials</topic><topic>Human Mesenchymal Stem Cells</topic><topic>Laser</topic><topic>Materials</topic><topic>Membranes cel·lulars</topic><topic>Pattern</topic><topic>Surface</topic><topic>Topography</topic><topic>Zirconi</topic><topic>Zirconia</topic><topic>Zirconium</topic><topic>Àrees temàtiques de la UPC</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stanciuc, Ana-Maria</creatorcontrib><creatorcontrib>Flamant, Quentin</creatorcontrib><creatorcontrib>Sprecher, Christoph Martin</creatorcontrib><creatorcontrib>Alini, Mauro</creatorcontrib><creatorcontrib>Anglada, Marc</creatorcontrib><creatorcontrib>Peroglio, Marianna</creatorcontrib><collection>CrossRef</collection><collection>Recercat</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Journal of the European Ceramic Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stanciuc, Ana-Maria</au><au>Flamant, Quentin</au><au>Sprecher, Christoph Martin</au><au>Alini, Mauro</au><au>Anglada, Marc</au><au>Peroglio, Marianna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions</atitle><jtitle>Journal of the European Ceramic Society</jtitle><date>2018-03</date><risdate>2018</risdate><volume>38</volume><issue>3</issue><spage>939</spage><epage>948</epage><pages>939-948</pages><issn>0955-2219</issn><eissn>1873-619X</eissn><abstract>Yttria-stabilised tetragonal zirconia polycrystals (3Y-TZP) bioinert ceramics combine excellent strength and toughness, good aesthetics, high resistance to corrosion and absence of allergic reaction. 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| source | ScienceDirect Journals (5 years ago - present); Recercat |
| subjects | Cell culture Cell membranes Engineering Sciences Enginyeria dels materials Human Mesenchymal Stem Cells Laser Materials Membranes cel·lulars Pattern Surface Topography Zirconi Zirconia Zirconium Àrees temàtiques de la UPC |
| title | Femtosecond laser multi-patterning of zirconia for screening of cell-surface interactions |
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