HLA‐DRB3/4/5 mismatches are associated with increased risk of acute GVHD in 10/10 matched unrelated donor hematopoietic cell transplantation

Matching for HLA‐A, ‐B, ‐C, and ‐DRB1 loci (8/8 match) is currently the gold standard for unrelated donor hematopoietic cell transplantation (HCT). In Europe, patients are also matched at the HLA‐DQB1 loci (10/10 match). However, there is increasing evidence that matching at HLA‐DRB3/4/5 loci may he...

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Veröffentlicht in:	American journal of hematology 2018-08, Vol.93 (8), p.994-1001
Hauptverfasser:	Ducreux, Stéphanie, Dubois, Valérie, Amokrane, Kahina, Yakoub‐Agha, Ibrahim, Labalette, Myriam, Michallet, Mauricette, Rubio, Marie‐Thérèse, Kennel, Anne, Forcade, Edouard, Lafarge, Xavier, Bulabois, Claude‐Eric, Masson, Dominique, Daguindau, Etienne, Devys, Anne, Moalic, Virginie, Quelvennec, Erwann, Boudifa, Abdelali, Picard, Christophe, Van Endert, Peter, de Matteis, Muriel, Delbos, Florent, Filloux, Matthieu, Pedron, Béatrice, Renac, Virginie, Hau, Françoise, Bonneau, Julie, Parissiadis, Anne, Fort, Marylise, Dormoy, Anne, Maillard, Natacha, Jollet, Isabelle, Chevallier, Patrice, Cesbron, Anne, Bay, Jacques‐Olivier, Quainon, Fabienne, Garnier, Federico, Socié, Gérard, Loiseau, Pascale, Porcher, Raphaël, Peffault de Latour, Régis
Format:	Artikel
Sprache:	eng
Schlagworte:	Drb1 protein Graft-versus-host reaction Hematology Histocompatibility antigen HLA Life Sciences Malignancy Morbidity Mortality Quality of life Stem cell transplantation Tissue typing Transplantation Transplants & implants
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