Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1

Chikungunya virus (CHIKV) is a re-emerging alphavirus transmitted to humans by Aedes mosquitoes. Since 2005, CHIKV has been spreading worldwide resulting in epidemics in Africa, the Indian Ocean islands, Asia and more recently in the Americas. CHIKV is thus considered as a global health concern. The...

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Veröffentlicht in:Antiviral research 2017-08, Vol.144, p.216-222
Hauptverfasser: Gigante, Alba, Gómez-SanJuan, Asier, Delang, Leen, Li, Changqing, Bueno, Oskía, Gamo, Ana-María, Priego, Eva-María, Camarasa, María-José, Jochmans, Dirk, Leyssen, Pieter, Decroly, Etienne, Coutard, Bruno, Querat, Gilles, Neyts, Johan, Pérez-Pérez, María-Jesús
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Sprache:eng
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