Ex vivo activity of Proveblue, a methylene blue, against field isolates of Plasmodium falciparum in Dakar, Senegal from 2013–2015

•Proveblue, a methylene blue preparation, was highly active against Plasmodium falciparum isolates (8.1 nM).•Proveblue was more active than standard antimalarial drugs, but less active than artemisinin derivatives.•A low significant positive correlation was found between Proveblue and artemisinin de...

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Veröffentlicht in:	International journal of antimicrobial agents 2017-08, Vol.50 (2), p.155-158
Hauptverfasser:	Fall, Bécaye, Madamet, Marylin, Diawara, Silman, Briolant, Sébastien, Wade, Khalifa Ababacar, Lo, Gora, Nakoulima, Aminata, Fall, Mansour, Bercion, Raymond, Kounta, Mame Bou, Amalvict, Rémi, Benoit, Nicolas, Gueye, Mamadou Wague, Diatta, Bakary, Wade, Boubacar, Pradines, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimalarial drug Antimalarials - pharmacology Enzyme Inhibitors - pharmacology Human health and pathology Humans In vitro Infectious diseases Inhibitory Concentration 50 Life Sciences Malaria Malaria, Falciparum - parasitology Methylene blue Methylene Blue - pharmacology Parasitic Sensitivity Tests Plasmodium falciparum Plasmodium falciparum - drug effects Plasmodium falciparum - isolation & purification Resistance Senegal
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