Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio
Dynamic guidance of living cells is achieved by fine-tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent...
Gespeichert in:
| Veröffentlicht in: | ACS applied materials & interfaces 2018-01, Vol.10 (3), p.2253-2258 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2258 |
|---|---|
| container_issue | 3 |
| container_start_page | 2253 |
| container_title | ACS applied materials & interfaces |
| container_volume | 10 |
| creator | Dalier, F Dubacheva, G. V Coniel, M Zanchi, D Galtayries, A Piel, M Marie, E Tribet, C |
| description | Dynamic guidance of living cells is achieved by fine-tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent PEG, RGD adhesion peptides, or T-responsive poly(N-isopropylacrylamide) strands. Deposition of mixed adlayers provides a straightforward mean to optimize complex substrates, which is here implemented to achieve (1) thermal control of ligand accessibility and (2) adjustment of relative adhesiveness between adjacent micropatterns, while preserving cell attachment during thermal cycles. The reversible polarization of HeLa cells along orthogonal stripes mimics guidance along natural matrices. |
| doi_str_mv | 10.1021/acsami.7b18513 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_hal_p</sourceid><recordid>TN_cdi_hal_primary_oai_HAL_hal_01730742v1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1989553276</sourcerecordid><originalsourceid>FETCH-LOGICAL-a404t-d20063d95dba254d7e6b43aa56bbfbbfd2ead85458a24b6faa06d1d1106c3df63</originalsourceid><addsrcrecordid>eNp1kE1LAzEQhoMoVqtXj5KjCq1JNtmP41LUChWhVvAWZjdZuyXb1GRb7b83ZWtvQiCZyTMPw4vQFSVDShi9h9JDUw-TgqaCRkfojGacD1Im2PHhzXkPnXu_ICSOGBGnqMeyiPIAnaGPl_pHKzyyK2u2jXY4Vwa22nmcG2O_6-UnnupNqOvCaDyba9eACfiyddZgW-G3gISfkTYG536lyxZPoa3tBTqpwHh9ub_76P3xYTYaDyavT8-jfDIATng7UGy3lcqEKoAJrhIdFzwCEHFRVOEopkGlgosUGC_iCoDEiipKSVxGqoqjPrrtvHMwcuXqBtxWWqjlOJ_IXY_QJCIJZxsa2JuOXTn7tda-lU3ty7A5LLVde0mzNBMiYslOO-zQ0lnvna4ObkrkLnnZJS_3yYeB6717XTRaHfC_qANw1wFhUC7s2i1DLP_ZfgGjrI22</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1989553276</pqid></control><display><type>article</type><title>Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio</title><source>American Chemical Society Journals</source><creator>Dalier, F ; Dubacheva, G. V ; Coniel, M ; Zanchi, D ; Galtayries, A ; Piel, M ; Marie, E ; Tribet, C</creator><creatorcontrib>Dalier, F ; Dubacheva, G. V ; Coniel, M ; Zanchi, D ; Galtayries, A ; Piel, M ; Marie, E ; Tribet, C</creatorcontrib><description>Dynamic guidance of living cells is achieved by fine-tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent PEG, RGD adhesion peptides, or T-responsive poly(N-isopropylacrylamide) strands. Deposition of mixed adlayers provides a straightforward mean to optimize complex substrates, which is here implemented to achieve (1) thermal control of ligand accessibility and (2) adjustment of relative adhesiveness between adjacent micropatterns, while preserving cell attachment during thermal cycles. The reversible polarization of HeLa cells along orthogonal stripes mimics guidance along natural matrices.</description><identifier>ISSN: 1944-8244</identifier><identifier>EISSN: 1944-8252</identifier><identifier>DOI: 10.1021/acsami.7b18513</identifier><identifier>PMID: 29314825</identifier><language>eng</language><publisher>United States: American Chemical Society</publisher><subject>Biotechnology ; Cell Behavior ; Cellular Biology ; Chemical Sciences ; Life Sciences ; Polymers</subject><ispartof>ACS applied materials & interfaces, 2018-01, Vol.10 (3), p.2253-2258</ispartof><rights>Copyright © 2018 American Chemical Society</rights><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a404t-d20063d95dba254d7e6b43aa56bbfbbfd2ead85458a24b6faa06d1d1106c3df63</citedby><cites>FETCH-LOGICAL-a404t-d20063d95dba254d7e6b43aa56bbfbbfd2ead85458a24b6faa06d1d1106c3df63</cites><orcidid>0000-0003-1417-5381 ; 0000-0002-5953-0968 ; 0000-0002-2848-177X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://pubs.acs.org/doi/pdf/10.1021/acsami.7b18513$$EPDF$$P50$$Gacs$$H</linktopdf><linktohtml>$$Uhttps://pubs.acs.org/doi/10.1021/acsami.7b18513$$EHTML$$P50$$Gacs$$H</linktohtml><link.rule.ids>230,314,780,784,885,2765,27076,27924,27925,56738,56788</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29314825$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.sorbonne-universite.fr/hal-01730742$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Dalier, F</creatorcontrib><creatorcontrib>Dubacheva, G. V</creatorcontrib><creatorcontrib>Coniel, M</creatorcontrib><creatorcontrib>Zanchi, D</creatorcontrib><creatorcontrib>Galtayries, A</creatorcontrib><creatorcontrib>Piel, M</creatorcontrib><creatorcontrib>Marie, E</creatorcontrib><creatorcontrib>Tribet, C</creatorcontrib><title>Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio</title><title>ACS applied materials & interfaces</title><addtitle>ACS Appl. Mater. Interfaces</addtitle><description>Dynamic guidance of living cells is achieved by fine-tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent PEG, RGD adhesion peptides, or T-responsive poly(N-isopropylacrylamide) strands. Deposition of mixed adlayers provides a straightforward mean to optimize complex substrates, which is here implemented to achieve (1) thermal control of ligand accessibility and (2) adjustment of relative adhesiveness between adjacent micropatterns, while preserving cell attachment during thermal cycles. The reversible polarization of HeLa cells along orthogonal stripes mimics guidance along natural matrices.</description><subject>Biotechnology</subject><subject>Cell Behavior</subject><subject>Cellular Biology</subject><subject>Chemical Sciences</subject><subject>Life Sciences</subject><subject>Polymers</subject><issn>1944-8244</issn><issn>1944-8252</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kE1LAzEQhoMoVqtXj5KjCq1JNtmP41LUChWhVvAWZjdZuyXb1GRb7b83ZWtvQiCZyTMPw4vQFSVDShi9h9JDUw-TgqaCRkfojGacD1Im2PHhzXkPnXu_ICSOGBGnqMeyiPIAnaGPl_pHKzyyK2u2jXY4Vwa22nmcG2O_6-UnnupNqOvCaDyba9eACfiyddZgW-G3gISfkTYG536lyxZPoa3tBTqpwHh9ub_76P3xYTYaDyavT8-jfDIATng7UGy3lcqEKoAJrhIdFzwCEHFRVOEopkGlgosUGC_iCoDEiipKSVxGqoqjPrrtvHMwcuXqBtxWWqjlOJ_IXY_QJCIJZxsa2JuOXTn7tda-lU3ty7A5LLVde0mzNBMiYslOO-zQ0lnvna4ObkrkLnnZJS_3yYeB6717XTRaHfC_qANw1wFhUC7s2i1DLP_ZfgGjrI22</recordid><startdate>20180124</startdate><enddate>20180124</enddate><creator>Dalier, F</creator><creator>Dubacheva, G. V</creator><creator>Coniel, M</creator><creator>Zanchi, D</creator><creator>Galtayries, A</creator><creator>Piel, M</creator><creator>Marie, E</creator><creator>Tribet, C</creator><general>American Chemical Society</general><general>Washington, D.C. : American Chemical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope><scope>VOOES</scope><orcidid>https://orcid.org/0000-0003-1417-5381</orcidid><orcidid>https://orcid.org/0000-0002-5953-0968</orcidid><orcidid>https://orcid.org/0000-0002-2848-177X</orcidid></search><sort><creationdate>20180124</creationdate><title>Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio</title><author>Dalier, F ; Dubacheva, G. V ; Coniel, M ; Zanchi, D ; Galtayries, A ; Piel, M ; Marie, E ; Tribet, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a404t-d20063d95dba254d7e6b43aa56bbfbbfd2ead85458a24b6faa06d1d1106c3df63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biotechnology</topic><topic>Cell Behavior</topic><topic>Cellular Biology</topic><topic>Chemical Sciences</topic><topic>Life Sciences</topic><topic>Polymers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dalier, F</creatorcontrib><creatorcontrib>Dubacheva, G. V</creatorcontrib><creatorcontrib>Coniel, M</creatorcontrib><creatorcontrib>Zanchi, D</creatorcontrib><creatorcontrib>Galtayries, A</creatorcontrib><creatorcontrib>Piel, M</creatorcontrib><creatorcontrib>Marie, E</creatorcontrib><creatorcontrib>Tribet, C</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Hyper Article en Ligne (HAL)</collection><collection>Hyper Article en Ligne (HAL) (Open Access)</collection><jtitle>ACS applied materials & interfaces</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dalier, F</au><au>Dubacheva, G. V</au><au>Coniel, M</au><au>Zanchi, D</au><au>Galtayries, A</au><au>Piel, M</au><au>Marie, E</au><au>Tribet, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio</atitle><jtitle>ACS applied materials & interfaces</jtitle><addtitle>ACS Appl. Mater. Interfaces</addtitle><date>2018-01-24</date><risdate>2018</risdate><volume>10</volume><issue>3</issue><spage>2253</spage><epage>2258</epage><pages>2253-2258</pages><issn>1944-8244</issn><eissn>1944-8252</eissn><abstract>Dynamic guidance of living cells is achieved by fine-tuning and spatiotemporal modulation on artificial polymer layers enabling reversible peptide display. Adjustment of surface composition and interactions is obtained by coadsorption of mixed poly(lysine) derivatives, grafted with either repellent PEG, RGD adhesion peptides, or T-responsive poly(N-isopropylacrylamide) strands. Deposition of mixed adlayers provides a straightforward mean to optimize complex substrates, which is here implemented to achieve (1) thermal control of ligand accessibility and (2) adjustment of relative adhesiveness between adjacent micropatterns, while preserving cell attachment during thermal cycles. The reversible polarization of HeLa cells along orthogonal stripes mimics guidance along natural matrices.</abstract><cop>United States</cop><pub>American Chemical Society</pub><pmid>29314825</pmid><doi>10.1021/acsami.7b18513</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-1417-5381</orcidid><orcidid>https://orcid.org/0000-0002-5953-0968</orcidid><orcidid>https://orcid.org/0000-0002-2848-177X</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1944-8244 |
| ispartof | ACS applied materials & interfaces, 2018-01, Vol.10 (3), p.2253-2258 |
| issn | 1944-8244 1944-8252 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_01730742v1 |
| source | American Chemical Society Journals |
| subjects | Biotechnology Cell Behavior Cellular Biology Chemical Sciences Life Sciences Polymers |
| title | Mixed Copolymer Adlayers Allowing Reversible Thermal Control of Single Cell Aspect Ratio |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T16%3A18%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_hal_p&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Mixed%20Copolymer%20Adlayers%20Allowing%20Reversible%20Thermal%20Control%20of%20Single%20Cell%20Aspect%20Ratio&rft.jtitle=ACS%20applied%20materials%20&%20interfaces&rft.au=Dalier,%20F&rft.date=2018-01-24&rft.volume=10&rft.issue=3&rft.spage=2253&rft.epage=2258&rft.pages=2253-2258&rft.issn=1944-8244&rft.eissn=1944-8252&rft_id=info:doi/10.1021/acsami.7b18513&rft_dat=%3Cproquest_hal_p%3E1989553276%3C/proquest_hal_p%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1989553276&rft_id=info:pmid/29314825&rfr_iscdi=true |