Incidence and prognostic significance of spontaneous and inducible antidromic tachycardia

Orthodromic atrioventricular reentrant tachycardia (ORT) is the most common arrhythmia at electrophysiological study (EPS) in patients with pre-excitation. The purpose of the study was to determine the clinical significance and the electrophysiological characteristics of patients with inducible anti...

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Veröffentlicht in:Europace (London, England) England), 2013-06, Vol.15 (6), p.871-876
Hauptverfasser: Brembilla-Perrot, Béatrice, Pauriah, Maheshwar, Sellal, Jean-Marc, Zinzius, Pierre Yves, Schwartz, Jérôme, de Chillou, Christian, Cismaru, Gabriel, Beurrier, Daniel, Voilliot, Damien, Selton, Olivier, Louis, Pierre, Andronache, Marius, Nosu, Radu, de la Chaise, Arnaud Terrier
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container_issue 6
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container_title Europace (London, England)
container_volume 15
creator Brembilla-Perrot, Béatrice
Pauriah, Maheshwar
Sellal, Jean-Marc
Zinzius, Pierre Yves
Schwartz, Jérôme
de Chillou, Christian
Cismaru, Gabriel
Beurrier, Daniel
Voilliot, Damien
Selton, Olivier
Louis, Pierre
Andronache, Marius
Nosu, Radu
de la Chaise, Arnaud Terrier
description Orthodromic atrioventricular reentrant tachycardia (ORT) is the most common arrhythmia at electrophysiological study (EPS) in patients with pre-excitation. The purpose of the study was to determine the clinical significance and the electrophysiological characteristics of patients with inducible antidromic tachycardia (ADT). Electrophysiological study was performed in 807 patients with a pre-excitation syndrome in control state and after isoproterenol. Antidromic tachycardia was induced in 63 patients (8%). Clinical and electrophysiological data were compared with those of 744 patients without ADT. Patients with and without ADT were similar in term of age (33 ± 18 vs. 34 ± 17), male gender (68 vs. 61%), clinical presentation with spontaneous atrioventricular reentrant tachycardia (AVRT) (35 vs. 42%), atrial fibrillation (AF) (3 vs. 3%), syncope (16 vs. 12%). In patients with induced ADT, asymptomatic patients were less frequent (24 vs. 37%;
doi_str_mv 10.1093/europace/eus354
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The purpose of the study was to determine the clinical significance and the electrophysiological characteristics of patients with inducible antidromic tachycardia (ADT). Electrophysiological study was performed in 807 patients with a pre-excitation syndrome in control state and after isoproterenol. Antidromic tachycardia was induced in 63 patients (8%). Clinical and electrophysiological data were compared with those of 744 patients without ADT. Patients with and without ADT were similar in term of age (33 ± 18 vs. 34 ± 17), male gender (68 vs. 61%), clinical presentation with spontaneous atrioventricular reentrant tachycardia (AVRT) (35 vs. 42%), atrial fibrillation (AF) (3 vs. 3%), syncope (16 vs. 12%). In patients with induced ADT, asymptomatic patients were less frequent (24 vs. 37%; <0.04), spontaneous ADT and spontaneous malignant form more frequent (8 vs. 0.5%; <0.001) (16 vs. 6%; <0.002). Left lateral accessory pathway (AP) location was more frequent (51 vs. 36%; P < 0.022), septal location less frequent (40 vs. 56%; P < 0.01). And 1/1 conduction through AP was more rapid. Orthodromic AVRT induction was as frequent (55.5 vs. 55%), but AF induction (41 vs. 24%; P < 0.002) and electrophysiological malignant form were more frequent (22 vs. 12%; P < 0.02). The follow-up was similar; four deaths and three spontaneous malignant forms occurred in patients without ADT. When population was divided based on age (<20/≥20 years), the older group was less likely to have criteria for malignant form. Antidromic tachycardia induction is rare in pre-excitation syndrome and generally is associated with spontaneous or electrophysiological malignant form, but clinical outcome does not differ.]]></description><identifier>ISSN: 1099-5129</identifier><identifier>EISSN: 1532-2092</identifier><identifier>DOI: 10.1093/europace/eus354</identifier><identifier>PMID: 23148120</identifier><language>eng</language><publisher>England: Oxford University Press (OUP)</publisher><subject>Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Cardiac Pacing, Artificial - statistics &amp; numerical data ; Child ; Child, Preschool ; Comorbidity ; Electrocardiography - statistics &amp; numerical data ; Electrophysiologic Techniques, Cardiac - statistics &amp; numerical data ; Female ; France - epidemiology ; Human health and pathology ; Humans ; Incidence ; Life Sciences ; Male ; Middle Aged ; Pre-Excitation Syndromes - diagnosis ; Pre-Excitation Syndromes - epidemiology ; Prognosis ; Reproducibility of Results ; Risk Assessment ; Sensitivity and Specificity ; Sexism ; Tachycardia, Atrioventricular Nodal Reentry - diagnosis ; Tachycardia, Atrioventricular Nodal Reentry - epidemiology ; Young Adult</subject><ispartof>Europace (London, England), 2013-06, Vol.15 (6), p.871-876</ispartof><rights>Distributed under a Creative Commons Attribution 4.0 International License</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-ae0c25b96922514ea9cb0def19889d3c3d7a85551e8c388504782e1ffa8cf6963</citedby><cites>FETCH-LOGICAL-c372t-ae0c25b96922514ea9cb0def19889d3c3d7a85551e8c388504782e1ffa8cf6963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,315,781,785,886,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23148120$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://hal.univ-lorraine.fr/hal-01718039$$DView record in HAL$$Hfree_for_read</backlink></links><search><creatorcontrib>Brembilla-Perrot, Béatrice</creatorcontrib><creatorcontrib>Pauriah, Maheshwar</creatorcontrib><creatorcontrib>Sellal, Jean-Marc</creatorcontrib><creatorcontrib>Zinzius, Pierre Yves</creatorcontrib><creatorcontrib>Schwartz, Jérôme</creatorcontrib><creatorcontrib>de Chillou, Christian</creatorcontrib><creatorcontrib>Cismaru, Gabriel</creatorcontrib><creatorcontrib>Beurrier, Daniel</creatorcontrib><creatorcontrib>Voilliot, Damien</creatorcontrib><creatorcontrib>Selton, Olivier</creatorcontrib><creatorcontrib>Louis, Pierre</creatorcontrib><creatorcontrib>Andronache, Marius</creatorcontrib><creatorcontrib>Nosu, Radu</creatorcontrib><creatorcontrib>de la Chaise, Arnaud Terrier</creatorcontrib><title>Incidence and prognostic significance of spontaneous and inducible antidromic tachycardia</title><title>Europace (London, England)</title><addtitle>Europace</addtitle><description><![CDATA[Orthodromic atrioventricular reentrant tachycardia (ORT) is the most common arrhythmia at electrophysiological study (EPS) in patients with pre-excitation. The purpose of the study was to determine the clinical significance and the electrophysiological characteristics of patients with inducible antidromic tachycardia (ADT). Electrophysiological study was performed in 807 patients with a pre-excitation syndrome in control state and after isoproterenol. Antidromic tachycardia was induced in 63 patients (8%). Clinical and electrophysiological data were compared with those of 744 patients without ADT. Patients with and without ADT were similar in term of age (33 ± 18 vs. 34 ± 17), male gender (68 vs. 61%), clinical presentation with spontaneous atrioventricular reentrant tachycardia (AVRT) (35 vs. 42%), atrial fibrillation (AF) (3 vs. 3%), syncope (16 vs. 12%). In patients with induced ADT, asymptomatic patients were less frequent (24 vs. 37%; <0.04), spontaneous ADT and spontaneous malignant form more frequent (8 vs. 0.5%; <0.001) (16 vs. 6%; <0.002). Left lateral accessory pathway (AP) location was more frequent (51 vs. 36%; P < 0.022), septal location less frequent (40 vs. 56%; P < 0.01). And 1/1 conduction through AP was more rapid. Orthodromic AVRT induction was as frequent (55.5 vs. 55%), but AF induction (41 vs. 24%; P < 0.002) and electrophysiological malignant form were more frequent (22 vs. 12%; P < 0.02). The follow-up was similar; four deaths and three spontaneous malignant forms occurred in patients without ADT. When population was divided based on age (<20/≥20 years), the older group was less likely to have criteria for malignant form. Antidromic tachycardia induction is rare in pre-excitation syndrome and generally is associated with spontaneous or electrophysiological malignant form, but clinical outcome does not differ.]]></description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cardiac Pacing, Artificial - statistics &amp; numerical data</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Comorbidity</subject><subject>Electrocardiography - statistics &amp; numerical data</subject><subject>Electrophysiologic Techniques, Cardiac - statistics &amp; numerical data</subject><subject>Female</subject><subject>France - epidemiology</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Incidence</subject><subject>Life Sciences</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Pre-Excitation Syndromes - diagnosis</subject><subject>Pre-Excitation Syndromes - epidemiology</subject><subject>Prognosis</subject><subject>Reproducibility of Results</subject><subject>Risk Assessment</subject><subject>Sensitivity and Specificity</subject><subject>Sexism</subject><subject>Tachycardia, Atrioventricular Nodal Reentry - diagnosis</subject><subject>Tachycardia, Atrioventricular Nodal Reentry - epidemiology</subject><subject>Young Adult</subject><issn>1099-5129</issn><issn>1532-2092</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kDtPwzAUhS0EoqUws6GOMIT6ESf2WFVAK1VigYHJcvxojRI7xAlS_z0JaTvdq3u_c6RzALhH8BlBThama0ItlemXSGh6AaaIEpxgyPFlv0POE4own4CbGL8hhDnm9BpMMEEpQxhOwdfGK6eNV2YuvZ7XTdj5EFun5tHtvLNOyeEX7DzWwbfSm9DFf9R53SlXlIOwdboJVS9qpdoflGy0k7fgysoymrvjnIHP15eP1TrZvr9tVsttokiO20QaqDAteMYxpig1kqsCamMRZ4xroojOJaOUIsMUYYzCNGfYIGslUzbjGZmBp9F3L0tRN66SzUEE6cR6uRXDDaIcMUj4L-rZx5Htc_50JraiclGZshxzCURoRjiEnPXoYkRVE2JsjD17IyiG7sWpezF23ysejuZdURl95k9lkz_x04Mc</recordid><startdate>20130601</startdate><enddate>20130601</enddate><creator>Brembilla-Perrot, Béatrice</creator><creator>Pauriah, Maheshwar</creator><creator>Sellal, Jean-Marc</creator><creator>Zinzius, Pierre Yves</creator><creator>Schwartz, Jérôme</creator><creator>de Chillou, Christian</creator><creator>Cismaru, Gabriel</creator><creator>Beurrier, Daniel</creator><creator>Voilliot, Damien</creator><creator>Selton, Olivier</creator><creator>Louis, Pierre</creator><creator>Andronache, Marius</creator><creator>Nosu, Radu</creator><creator>de la Chaise, Arnaud Terrier</creator><general>Oxford University Press (OUP)</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>1XC</scope></search><sort><creationdate>20130601</creationdate><title>Incidence and prognostic significance of spontaneous and inducible antidromic tachycardia</title><author>Brembilla-Perrot, Béatrice ; 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The purpose of the study was to determine the clinical significance and the electrophysiological characteristics of patients with inducible antidromic tachycardia (ADT). Electrophysiological study was performed in 807 patients with a pre-excitation syndrome in control state and after isoproterenol. Antidromic tachycardia was induced in 63 patients (8%). Clinical and electrophysiological data were compared with those of 744 patients without ADT. Patients with and without ADT were similar in term of age (33 ± 18 vs. 34 ± 17), male gender (68 vs. 61%), clinical presentation with spontaneous atrioventricular reentrant tachycardia (AVRT) (35 vs. 42%), atrial fibrillation (AF) (3 vs. 3%), syncope (16 vs. 12%). In patients with induced ADT, asymptomatic patients were less frequent (24 vs. 37%; <0.04), spontaneous ADT and spontaneous malignant form more frequent (8 vs. 0.5%; <0.001) (16 vs. 6%; <0.002). Left lateral accessory pathway (AP) location was more frequent (51 vs. 36%; P < 0.022), septal location less frequent (40 vs. 56%; P < 0.01). And 1/1 conduction through AP was more rapid. Orthodromic AVRT induction was as frequent (55.5 vs. 55%), but AF induction (41 vs. 24%; P < 0.002) and electrophysiological malignant form were more frequent (22 vs. 12%; P < 0.02). The follow-up was similar; four deaths and three spontaneous malignant forms occurred in patients without ADT. When population was divided based on age (<20/≥20 years), the older group was less likely to have criteria for malignant form. Antidromic tachycardia induction is rare in pre-excitation syndrome and generally is associated with spontaneous or electrophysiological malignant form, but clinical outcome does not differ.]]></abstract><cop>England</cop><pub>Oxford University Press (OUP)</pub><pmid>23148120</pmid><doi>10.1093/europace/eus354</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Access via Oxford University Press (Open Access Collection); EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection
subjects Adolescent
Adult
Age Distribution
Aged
Aged, 80 and over
Cardiac Pacing, Artificial - statistics & numerical data
Child
Child, Preschool
Comorbidity
Electrocardiography - statistics & numerical data
Electrophysiologic Techniques, Cardiac - statistics & numerical data
Female
France - epidemiology
Human health and pathology
Humans
Incidence
Life Sciences
Male
Middle Aged
Pre-Excitation Syndromes - diagnosis
Pre-Excitation Syndromes - epidemiology
Prognosis
Reproducibility of Results
Risk Assessment
Sensitivity and Specificity
Sexism
Tachycardia, Atrioventricular Nodal Reentry - diagnosis
Tachycardia, Atrioventricular Nodal Reentry - epidemiology
Young Adult
title Incidence and prognostic significance of spontaneous and inducible antidromic tachycardia
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