Organ preservation for rectal cancer (GRECCAR 2): a prospective, randomised, open-label, multicentre, phase 3 trial

Summary Background Organ preservation is a concept proposed for patients with rectal cancer after a good clinical response to neoadjuvant chemotherapy, to potentially avoid morbidity and side-effects of rectal excision. The objective of this study was to compare local excision and total mesorectal e...

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Veröffentlicht in:	The Lancet (British edition) 2017-07, Vol.390 (10093), p.469-479
Hauptverfasser:	Rullier, Eric, Prof, Rouanet, Philippe, Prof, Tuech, Jean-Jacques, Prof, Valverde, Alain, MD, Lelong, Bernard, Prof, Rivoire, Michel, Prof, Faucheron, Jean-Luc, Prof, Jafari, Mehrdad, Prof, Portier, Guillaume, Prof, Meunier, Bernard, Prof, Sileznieff, Igor, Prof, Prudhomme, Michel, Prof, Marchal, Frédéric, Prof, Pocard, Marc, Prof, Pezet, Denis, Prof, Rullier, Anne, MD, Vendrely, Véronique, MD, Denost, Quentin, MD, Asselineau, Julien, PhD, Doussau, Adélaïde, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Bacteriology Biochemistry, Molecular Biology Cancer surgery Chemoradiotherapy Chemoradiotherapy, Adjuvant - methods Chemotherapy Clinical trials Colorectal cancer Evidence-based medicine Female Health risk assessment Humans Internal Medicine Kaplan-Meier Estimate Life Sciences Male Medical prognosis Metastases Microbiology and Parasitology Middle Aged Molecular biology Morbidity Neoadjuvant Therapy - methods Neoplasm Staging Organ Preservation - methods Patients Pharmaceuticals Postoperative Complications - prevention & control Prospective Studies Radiation therapy Rectal Neoplasms - pathology Rectal Neoplasms - surgery Rectal Neoplasms - therapy Rectum Recurrence Side effects Surgical outcomes Surgical techniques Treatment Outcome Tumors
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