Fixed-Dose Combination Therapy With Daclatasvir, Asunaprevir, and Beclabuvir for Noncirrhotic Patients With HCV Genotype 1 Infection

IMPORTANCE: The antiviral activity of all-oral, ribavirin-free, direct-acting antiviral regimens requires evaluation in patients with chronic hepatitis C virus (HCV) infection. OBJECTIVE: To determine the rates of sustained virologic response (SVR) in patients receiving the 3-drug combination of dac...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 2015-05, Vol.313 (17), p.1728-1735
Hauptverfasser:	Poordad, Fred, Sievert, William, Mollison, Lindsay, Bennett, Michael, Tse, Edmund, Bräu, Norbert, Levin, James, Sepe, Thomas, Lee, Samuel S, Angus, Peter, Conway, Brian, Pol, Stanislas, Boyer, Nathalie, Bronowicki, Jean-Pierre, Jacobson, Ira, Muir, Andrew J, Reddy, K. Rajender, Tam, Edward, Ortiz-Lasanta, Grisell, de Lédinghen, Victor, Sulkowski, Mark, Boparai, Navdeep, McPhee, Fiona, Hughes, Eric, Swenson, E. Scott, Yin, Philip D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alanine Transaminase - blood Antiviral Agents - administration & dosage Antiviral Agents - adverse effects Benzazepines - administration & dosage Clinical outcomes Drug Therapy, Combination Female Genotype Genotype & phenotype Hepacivirus - genetics Hepatitis Hepatitis C virus Hepatitis C, Chronic - drug therapy Hepatitis C, Chronic - virology Humans Imidazoles - administration & dosage Indoles - administration & dosage Inhibitor drugs Isoquinolines - administration & dosage Life Sciences Male Middle Aged Sulfonamides - administration & dosage Virology
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